Dr. Begg's current research interests are in the areas of cancer epidemiology, health services research, and in statistical methods that support these and other research projects. He has been pursuing the idea that studies of patients with multiple primary malignancies can be uniquely informative about cancer risk. This research encompasses inferences that can be drawn from the descriptive epidemiology of second primaries, and new analytic study designs that seek to recruit incident cases of second primary cancers, the prototype study being the international GEM investigation of melanoma (PI, Marianne Berwick). He has also been engaged in health services research that seeks to examine variations in patterns of care and outcomes, with an emphasis on studies linking surgical volume with mortality and other patient outcomes. Currently he is studying methods for estimating penetrance of cancer in individuals at high genetic risk.
Career Opportunities
Including Cancer Epidemiologist,
Health Outcomes faculty,
Research Biostatistician, and Application Analyst
Begg CB. The search for cancer risk factors: when can we stop looking? (with commentaries) Am J Public Health 2001;91:360-364.
Begg CB, Riedel ER, Bach PB, Kattan MW, Schrag D, Warren JL, Scardino PT. Variations in morbidity following radical prostatectomy (with editorial). New Engl J Med 2002; 346:1138-1144.
Begg CB. On the use of familial aggregation in population-based case probands for calculating penetrance (with editorial). J Natl Cancer Inst 2002;94:1221-1226.
Begg CB, Orlow I, Hummer AJ, Armstrong BK, Kricker A, Marrett LD, Millikan RC, Gruber SB, Anton-Culver H, Zanetti R, Gallagher RP, Dwyer T, Rebbeck TR, Mitra N, Busam K, From L, Berwick M. Lifetime risk of melanoma in CDKN2A mutation carriers in a population-based sample (with editorial). J Natl Cancer Inst 2005;97:1507-15.
Begg CB, Hummer AJ, Mujumdar U, Armstrong BK, Kricker A, Marrett LD, Millikan RC, Gruber SB, Culver HA, Zanetti R, Gallagher RP, Dwyer T, Rebbeck TR, Klaus Busam, From L, Berwick M. A design for cancer case-control studies using only incident cases: experience with the GEM study of melanoma. Int. J. Epidemiol; 2006; 35: 756-764.
