Major Research Areas

The immune system represents a complex, interacting set of cells and molecules, controlled by defined genes and their products. Immunology provides the basis for a whole range of problems for other disciplines, including cell biology, structural biology, genetics, and medicine. Thus, immunology is a discipline that crosses through and integrates multiple disciplines of biology and medicine.

The scope of immunology at the Sloan-Kettering Institute incorporates a range of areas and expertise (both basic and translational science). A strength of the Immunology Program is the ability to translate laboratory findings into effective clinical applications. Research in the Immunology Program focuses on several areas:

  • cell signaling
  • development in the thymus
  • T cell selection
  • antigen processing and presentation
  • genetic approaches to transplantation and active immunization
  • cancer immunology
  • infection and immunity
  • transplantation immunology
  • adoptive cellular therapies

James P. Allison
Program Chairman
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