Neurons created from embryonic stem cells
In the Lab
By Julie Grisham, MS, Science Writer/Editor  |  Thursday, January 22, 2015

A new tool called optogenetics is revealing clues about the function of a promising experimental therapy derived from stem cells.

Sandra D’Angelo and Jedd Wolchok
In the Clinic
By Jim Stallard, MA, Writer/Editor  |  Tuesday, January 6, 2015

A new treatment for advanced melanoma is the latest promising advance in immunotherapy tested in large part by our scientists.

Stained pathology slides of a patient’s tumor (right) and of an organoid made from that tumor (left).
In the Lab
By Christina Pernambuco-Holsten, MA, Managing Web Editor  |  Tuesday, December 30, 2014

From tropical plants and 3-D snapshots of worms to tiny particles that light up tumors, here’s a glimpse at some of the fascinating work MSK researchers pursued in 2014 as part of our quest to advance cancer science.

Pictured: Eytan Stein
In the Clinic
By Julie Grisham, MS, Science Writer/Editor  |  Thursday, December 11, 2014

An experimental drug for blood cancers with certain genetic mutations is showing promise in early-stage trials.

Pictured: Viviane Tabar
In the Lab
By Julie Grisham, MS, Science Writer/Editor  |  Monday, December 1, 2014

Investigators have created the first-ever genetically engineered model of cancer made from human embryonic stem cells in culture.

Michel Sadelain and Prasad Adusumilli
Finding
By Julie Grisham, MS, Science Writer/Editor  |  Wednesday, November 19, 2014

A study in mouse models suggests how modified T cells may be used to treat tumors in the area just outside the lungs.

(From left) MSK investigators Michael Berger, José Baselga, and Maurizio Scaltriti, and graduate student Pau Castel.
Finding
By Julie Grisham, MS, Science Writer/Editor  |  Monday, November 17, 2014

A study of one patient’s disease has clarified why tumors stop responding to a class of experimental drugs called PI3K inhibitors.

Pictured: William Lee, Chris Sander & Nils Weinhold
In the Lab
By Julie Grisham, MS, Science Writer/Editor  |  Thursday, November 13, 2014

In a study of patient tumor samples, researchers have found common mutations in parts of the genome that control gene regulation.

Pictured: Joao Xavier & Eric Pamer
In the Lab
By Julie Grisham, MS, Science Writer/Editor  |  Monday, November 10, 2014

Clostridium difficile infections are a growing problem, but MSK researchers are looking for innovative ways to prevent and treat them.

Cancer biologist Andrea Ventura
In the Lab
By Eva Kiesler, PhD, Science Writer/Editor  |  Thursday, November 6, 2014

For the first time, Memorial Sloan Kettering scientists have created a mouse model that replicates a subtype of non-small cell lung cancer caused by a chromosomal rearrangement — a type of mutation that is common in cancers but thus far has been very difficult to study.

Pictured: Jorge Reis-Filho and Britta Weigelt
In the Lab
By Jim Stallard, MA, Writer/Editor  |  Tuesday, October 28, 2014

Genetic alterations linked to a rare salivary cancer could also shed light on more common malignancies.

Pictured: Pseudomonas aeruginosa
In the Lab
By Jim Stallard, MA, Writer/Editor  |  Tuesday, October 21, 2014

MSK researchers discover that the body senses and attacks harmful bacteria indirectly after the pathogens cause stress within the cells.

Pictured: Ping Chi
In the Lab
By Julie Grisham, MS, Science Writer/Editor  |  Thursday, October 9, 2014

Genetic analysis reveals biomarkers and possible drug targets for malignant peripheral nerve sheath tumors.

Pictured: Scott Lowe
In the Lab
By Eva Kiesler, PhD, Science Writer/Editor  |  Tuesday, September 30, 2014

In taking a new approach to finding treatments for hepatocellular carcinoma, MSK scientists have uncovered a potential drug target for this highly aggressive cancer.

Pictured: Experimental Brain Tumor
In the Lab
By Julie Grisham, MS, Science Writer/Editor  |  Thursday, September 18, 2014

Researchers have engineered a gene into therapeutic cells that allows them to turn off tumor growth if some of the cells become cancerous.

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