I am a board-certified medical oncologist and internist and Chief of Memorial Sloan-Kettering’s Melanoma and Sarcoma Service. I am also a professor of medicine at Weill Cornell Medical College. In addition, I direct the Laboratory of New Drug Development, which focuses on the identification of new targeted agents for cancer therapy, especially in the treatment of sarcoma and melanoma. However, these agents are not disease specific and hold promise in the treatment of all solid-tumor malignancies. These laboratory studies allow for a bridge between the laboratory and the clinic, and many of the drugs that originated in the lab are now being evaluated in clinical trials. My research studies have been supported by the National Cancer Institute, the Lustgarten Foundation for Pancreatic Cancer, the Department of Defense for Breast Cancer Research, the Byrne Foundation, the Food and Drug Administration, and the generous philanthropic support of Memorial Sloan-Kettering's patients and their families.