Brain Tumors, Primary: Our Clinical Trials

In addition to providing excellent care, physicians at the Brain Tumor Center are constantly working to improve treatment for brain tumors. An important part of this effort takes place in our clinical trials, which investigate a wide range of new approaches to diagnosis and treatment.

Clinical trials offer the best treatment options for many people with brain tumors, either as a first-line approach, or if you have a brain tumor that is not responding positively to other therapies. Our experts can help to determine which clinical trials are right for you.

Because doctors from different disciplines work together closely at the Brain Tumor Center, many of our clinical trials combine different treatment approaches, such as radiation therapy and chemotherapy. These aggressive approaches show promise for improving the treatment of many types of brain tumors.

As a member of the North American Brain Tumor Consortium — a brain tumor research group sponsored by the National Cancer Institute (NCI) — the Brain Tumor Center also offers qualified patients access to several NCI-sponsored clinical trials, in addition to our own protocols. We are also the lead institution on many brain cancer clinical trials nationwide and around the world.

Showing 12 trials
Titlesort icon Investigator
A Phase I Study of Carboxyamidotriazole Orotate Plus Temozolomide in Patients with Glioblastoma Multiforme and Other Recurrent Malignant Gliomas
[Protocol 12-007]
Omuro, Antonio, MD
A Phase I Study of Hypofractionated Stereotactic Radiosurgery with Bevacizumab to Treat Recurrent Malignant Glioma
[Protocol 11-057]
Omuro, Antonio, MD
A Phase I Study of MK-1775 with Radiation Therapy and Temozolomide in Patients with Newly Diagnosed Glioblastoma
Newly Diagnosed
[Protocol 13-161]
Kaley, Thomas, MD
A Phase I Study of Oral AG-120 in Patients with Advanced Solid Tumors, Including Glioma, with an IDH1 Mutation
[Protocol 14-068]
Mellinghoff, Ingo, MD
A Phase I Study of Pomalidomide in Patients with Recurrent or Persistent Primary Central Nervous System Lymphoma or Primary Vitreoretinal Lymphoma
[Protocol 14-003]
Grommes, Christian, MD
A Phase II Study of Carboplatin and Bevacizumab for the Treatment of Recurrent Low-Grade and Anaplastic Ependymoma in Adults
[Protocol 11-146]
Omuro, Antonio, MD
A Phase II Study of MEDI4736 in Patients with Glioblastoma
Newly Diagnosed & Relapsed/Refractory
[Protocol 14-258]
Kaley, Thomas, MD
A Phase IIB Study of Nivolumab Alone or with Ipilimumab in Patients with Recurrent Glioblastoma
[Protocol 14-009]
Omuro, Antonio, MD
A Phase III Study of Armodafinil versus Placebo to Reduce Cancer-Related Fatigue in Patients with High-Grade Glioma
Newly Diagnosed & Relapsed/Refractory
[Protocol 14-040]
Diamond, Eli, MD
A Pilot Study of NovoTTF-100A for Recurrent Atypical or Anaplastic Meningioma
[Protocol 13-067]
Kaley, Thomas, MD
Genetics of Treatment-Related Cognitive and Brain Structural Changes in Brain Tumor Survivors
[Protocol 09-151]
Correa, Denise, PhD
Prognostic Awareness and Patient-Physician Communication in Malignant Glioma
[Protocol 13-253]
Diamond, Eli, MD