I am a board-certified medical oncologist whose clinical practice is devoted to the care of patients with breast cancer, and I work as part of a multidisciplinary team to treat women with this disease. My research activities are focused on developing new therapeutic approaches for the treatment of breast cancer, and investigating the impact of these therapies on fertility and sexual health.
Currently, I am involved in clinical trials to evaluate anti-angiogenic agents, which are designed to cut off the tumor’s blood supply. In addition, I am investigating therapies that interfere with estrogen in women with hormone-receptor-positive breast cancer, and therapies that are targeted to other growth factor signaling pathways (e.g. the HER2 pathway). My colleagues and I are investigating these approaches when they are given alone or in combination (for example, giving both anti-estrogen therapy and anti-angiogenic therapy). I am also involved in clinical trials evaluating the effects of breast cancer therapy (e.g. chemotherapy) on ovarian reserve in premenopausal women, and the use of low dose intravaginal estrogen to ameliorate symptoms of vaginal dryness in postmenopausal women.