Protocol
10-025
Full Title
Pilot Study of Multi-Beam Intensity-Modulated Radiation Therapy for Node-Positive Breast Cancer Patients Requiring Treatment of the Internal Mammary Lymph Nodes
Purpose
The purpose of this study is to evaluate the safety of a new radiation treatment called “multi-beam intensity-modulated radiation therapy” ( IMRT) in women with breast cancer that has spread to the lymph nodes and who need radiation therapy after surgery. Currently, the standard way of giving radiation is using simplified IMRT, which uses only two beams of radiation.
Multi-beam IMRT works by using six to ten small radiation beams to give a more tailored radiation dose to the breast, chest wall, and the lymph nodes. At the same time, multi-beam IMRT may result in a lower dose of radiation to the heart, lungs, and nearby tissue, especially when the internal mammary lymph nodes need to be targeted by radiation.
Investigator
Co-Investigators
Eligibility
To be eligible for this study, patients must meet several criteria, including but not limited to the following:
- Patients must have a confirmed diagnosis of invasive breast cancer that has spread to at least one regional lymph node, but not to distant sites.
- Patients must be female.
- Patients may not have had prior radiation therapy to either breast.
- Patients must be age 18 or older
For more information about this study and to inquire about eligibility, please contact Dr. Alice Ho at 212-639-6773.
Disease(s)
Breast Cancer
Locations
ClinicalTrials.gov
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