Protocol
10-114
Full Title
A Phase II Study of Partial Breast Irradiation (PBI) Using 40 Gy for Select Patients with Early Invasive or Noninvasive Breast Cancer
Purpose
The standard of care for treating early-stage invasive breast cancer or ductal carcinoma in situ (DCIS) is a combination of lumpectomy and radiotherapy. The traditional method of giving radiation therapy after a lumpectomy is to direct it to the whole breast. With partial breast irradiation (PBI), the radiation is given only to the area of the breast where the cancer was removed.
The purpose of this study is to determine the side effects and effectiveness of delivering PBI instead of whole breast irradiation (WBI) in women with early-stage breast cancer or DCIS. Another purpose of this study is to examine the rate of recurrence of cancer in the same breast as the original cancer in patients who receive PBI.
With WBI, radiation therapy is given five days a week for five to seven weeks. With PBI, radiation therapy is given for a few minutes a day, once a day, five days a week for two weeks.
Investigator
Co-Investigators
Eligibility
To be eligible for this study, patients must meet several criteria, including but not limited to the following:
- Patients must have DCIS or stage I breast cancer and may not have previously received radiation therapy to the breast or chest.
- Patients must be fully active and capable of carrying on all regular activities without restrictions.
- Patients must be age 18 or older.
For more information about this study and to inquire about eligibility, please contact Dr. Simon Powell at 212-639-6072.
Disease(s)
Breast Cancer
Locations
ClinicalTrials.gov
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