Breast Cancer: Our Clinical Trials

You may be offered the opportunity to take part in a clinical trial at some point during your treatment. Clinical trials are research studies that evaluate the safety and effectiveness of new treatment approaches for diseases. In some cases, a study may give you access to new therapies that are not yet readily available. Clinical trials may also be used to compare diagnostic tests, prevention strategies, or other aspects of care for cancer patients. Learn more about clinical trials.

Below is a listing of breast cancer clinical trials that are currently enrolling patients at Memorial Sloan Kettering Cancer Center.

Showing 1 - 50 of 60 trials
Titlesort icon Investigator
A Long-Term Study of Sexual and Reproductive Health in Women with Breast Cancer and Lymphoma
[Protocol 12-249]
Goldfarb, Shari, MD
A Multicenter Phase II Study of Docosahexaenoic Acid (DHA) in Patients with a History of Breast Cancer, Premalignant Lesions, or Benign Breast Disease
[Protocol 12-267]
Hudis, Clifford, MD
A Phase I Study of ARN-810 in Postmenopausal Women with Locally Advanced or Metastatic Estrogen Receptor-Positive Breast Cancer
[Protocol 13-049]
Dickler, Maura, MD
A Phase I Study of BKM120 and Olaparib in Patients with High-Grade Serous Ovarian Cancer
[Protocol 12-233]
Bell-McGuinn, Katherine, MD, PhD
A Phase I Study of BYL719 with Letrozole or Exemestane for Treating Locally Advanced Inoperable or Metastatic Breast Cancer
[Protocol 13-027]
Dickler, Maura, MD
A Phase I Study of CB-839 in Patients with Advanced Solid Tumors
[Protocol 14-111]
Harding, James, MD
A Phase I Study of Debio1347 in Patients with Advanced Cancers Containing FGFR Alterations
[Protocol 13-131]
Voss, Martin, MD
A Phase I Study of DLYE5953A in Patients with Advanced or Persistent Solid Tumors
[Protocol 14-089]
Modi, Shanu, MD
A Phase I Study of Enzalutamide (MDV3100) in Patients with Previously Treated Metastatic Breast Cancer
[Protocol 12-155]
Traina, Tiffany, MD
A Phase I Study of Ganetespib with Paclitaxel and Trastuzumab in Women with Metastatic Breast Cancer
[Protocol 13-168]
Modi, Shanu, MD
A Phase I Study of GL-ONC1 for Treating Malignant Pleural Effusion
[Protocol 12-169]
Rusch, Valerie, MD
A Phase I Study of LJM716, BYL719, and Trastuzumab in Women with Metastatic HER2-Positive Breast Cancer
[Protocol 14-057]
Modi, Shanu, MD
A Phase I Study of Lurbinectedin plus Paclitaxel in Patients with Advanced Solid Tumors
[Protocol 13-170]
Drilon, Alexander, MD
A Phase I Study of SGN-LIV1A in Women with Metastatic Breast Cancer
[Protocol 14-013]
Modi, Shanu, MD
A Phase I Study of Topical Calcitriol (Compound 31543) to Prevent Hair Loss in Women Receiving Paclitaxel for Advanced Breast Cancer
[Protocol 11-205]
Lacouture, Mario, MD
A Phase I Study of Whole Brain Radiation Therapy plus Sorafenib for Patients with Breast Cancer Brain Metastases
[Protocol 12-046]
Seidman, Andrew, MD
A Phase I-II Study of Dasatinib plus Paclitaxel in Patients with Metastatic Breast Cancer
[Protocol 08-122]
Fornier, Monica, MD
A Phase I/II Clinical Trial of Temsirolimus plus Neratinib for Subjects with Metastatic HER2-Amplified or Triple-Negative Breast Cancer
[Protocol 10-005]
Chandarlapaty, Sarat, MD, PhD
A Phase I/II Study of Intrathecal Trastuzumab in Women with HER2-Positive Breast Cancer that Spread to the Spinal Fluid
[Protocol 12-123]
Pentsova, Elena, MD
A Phase I/II Study of Nivolumab Alone and with Ipilimumab in Patients with Advanced or Metastatic Solid Tumors
Relapsed/Refractory
[Protocol 13-187]
Callahan, Margaret, MD, PhD
A Phase IA/IB Study of RO5509554 Alone and with Paclitaxel in Patients with Advanced Solid Tumors
[Protocol 14-086]
D'Angelo, Sandra, MD
A Phase IB Study of LEE011 and Exemestane with and without Everolimus in Women with Locally Advanced or Metastatic Breast Cancer
[Protocol 13-179]
Modi, Shanu, MD
A Phase IB Study of LY2835219 plus Hormonal Therapy in Women with Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer
[Protocol 14-085]
Dickler, Maura, MD
A Phase Ib Study of Oral BGJ398 and BYL719 in Patients with Certain Advanced Solid Tumors
[Protocol 13-246]
Fury, Matthew, MD, PhD
A Phase II Study of BYL719 plus AMG 479 (Ganitumab) in Patients with Advanced Ovarian Cancer or Hormone Receptor-Positive Breast Cancer
[Protocol 13-251]
Modi, Shanu, MD
A Phase II Study of Cabozantinib in Women with Hormone Receptor-Positive Breast Cancer that Spread to the Bone
[Protocol 12-091]
Fornier, Monica, MD
A Phase II Study of Capecitabine with Lapatinib or Neratinib in Patients with Metastatic HER2-Positive Breast Cancer
[Protocol 13-121]
Latif, Asma, MD
A Phase II Study of Dose-Dense Doxorubicin and Cyclophosphamide followed by Eribulin Mesylate for the Adjuvant Treatment of Early-Stage Breast Cancer
[Protocol 10-190]
Traina, Tiffany, MD
A Phase II Study of Exemestane with and without Enzalutamide in Women with Advanced Hormone Receptor-Positive Breast Cancer
[Protocol 13-257]
Traina, Tiffany, MD
A Phase II Study of Fulvestrant Alone or with GDC-0941 or GDC-0980 in Women with Advanced Breast Cancer Resistant to Aromatase Inhibitor Therapy
[Protocol 12-029]
Dickler, Maura, MD
A Phase II Study of Multi-Beam Intensity-Modulated Radiation Therapy for Patients with Locally Advanced Breast Cancer Who Had Implant Reconstruction
[Protocol 14-028]
Ho, Alice, MD
A Phase II Study of Neratinib to Treat Metastatic Breast Cancer that Does Not Overexpress HER2 but Has a HER2 Mutation
[Protocol 13-195]
Modi, Shanu, MD
A Phase II Study of SNX-5422 in Patients with Select Advanced HER2 Cancers
[Protocol 13-112]
Voss, Martin, MD
A Phase II Study of Veliparib plus Temozolomide, Veliparib plus Carboplatin and Paclitaxel, or Carboplatin and Paclitaxel with Placebo in Patients with BRCA Mutations and Metastatic Breast Cancer
[Protocol 12-122]
Robson, Mark, MD
A Phase II Study to See if Carvedilol Can Help Prevent Heart Function Problems in Women Receiving Anthracyclines or Anti-HER2 Therapies for Breast Cancer
[Protocol 14-099]
Yu, Anthony, MD
A Phase III Study Comparing Mometasone Furoate with Eucerin to Treat Radiation-Related Skin Redness and Peeling in Breast Cancer Patients after Mastectomy
[Protocol 13-069]
Olm-Shipman, Molly, RN
A Phase III Study Evaluating of the Role of Axillary (Armpit) Lymph Node Removal in Patients with Breast Cancer with Positive Sentinel Lymph Nodes after Preoperative Chemotherapy
Newly Diagnosed
[Protocol 14-151]
King, Tari, MD
A Phase III Study of BKM120 with Fulvestrant in Postmenopausal Women with Locally Advanced or Metastatic Hormone Receptor-Positive HER2-Negative Breast Cancer
[Protocol 12-290]
Dickler, Maura, MD
A Phase III Study of Hormone Therapy with and without Chemotherapy in Patients with HER2-Negative Breast Cancer and 1-3 Positive Lymph Nodes and a Recurrence Score of 25 or Less
[Protocol 12-118]
Lake, Diana, MD
A Phase III Study of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer
[Protocol 11-190]
King, Tari, MD
A Pilot Study of a Geriatric-Specific Psychoeducational Intervention for Elderly Cancer Patients
[Protocol 09-116]
Roth, Andrew, MD
A Study Assessing the Use of Dual Handset Phones to Improve Communication with Inpatients Who Have Limited English Proficiency
[Protocol 14-042]
Kumar, Chhavi, MD
A Study Comparing Whole Breast Screening Ultrasound with 3D Mammography (Digital Breast Tomosynthesis) in Women Scheduled for Digital Mammography and Ultrasound
Newly Diagnosed & Relapsed/Refractory
[Protocol 14-119]
Sung, Janice, MD
A Study of Non-Hormonal Vaginal Moisturizer in Hormone Receptor-Positive Postmenopausal Cancer Survivors
[Protocol 12-232]
Carter, Jeanne, PhD
Acupuncture for Chronic Lymphedema After Breast Cancer Treatment
[Protocol 12-210]
Cassileth, Barrie, PhD
Assessment of a Customized Computer Program for Reducing Fears of Breast Cancer Recurrence
[Protocol 11-204]
Lichtenthal, Wendy, PhD
Clinical and Biological Predictors of Chemotherapy Toxicity in Older Adults
[Protocol 12-089]
Tew, William, MD
Clinical Significance of Germline BRCA Mutations
[Protocol 96-051]
Offit, Kenneth, MD
Cognition in Older Breast Cancer Survivors: Influence of Treatment, Genetics, and Smoking History
[Protocol 14-071]
Ahles, Tim, PhD
Development of Group Interventions for Breast Cancer Survivors
[Protocol 12-291]
Lichtenthal, Wendy, PhD