Cancer of Unknown Primary Origin: Diagnosis & Treatment at Memorial Sloan Kettering

Each year, more than 500 patients with an initial diagnosis of cancer of unknown primary origin (CUP) seek treatment at Memorial Sloan Kettering Cancer Center. Our multidisciplinary team of experts uses sophisticated imaging technologies, advanced molecular profiling, and other laboratory tests to learn as much as possible about these tumors. Sometimes, doctors can determine the primary site with near certainty. When it is not possible to identify the primary site, we can identify features of the tumor that can help to determine the best treatment plan.

Learn more about our approach to the diagnosis and treatment of cancer of unknown primary origin.