Lung Cancer, Non-Small Cell : Our Clinical Trials

In addition to providing excellent care, Memorial Sloan-Kettering is constantly working to improve treatment for non-small cell lung cancer. Our physicians lead a large number of clinical trials that test new drugs and drug combinations, surgical and radiation therapy techniques, innovative diagnostic technologies, and strategies for preserving quality of life during and after treatment. This means that choosing Memorial Sloan-Kettering for your care may give you access to new treatment options before they are widely available elsewhere.

Our experts can help to determine which clinical trials are right for you. For more information about our clinical trials, call our physician referral service at 1-866-MSK-LUNG (1-866-675-5864), or talk with your doctor.

The following clinical trials for non-small cell lung cancer are currently enrolling new patients. For more information about a study, choose from the list below. Learn more about clinical trials.

Showing 23 trials
Title Investigator
A Phase I Study of Afatinib with Chemotherapy and Radiation Therapy in Patients with EGFR-Mutant Non-Small Cell Lung Cancer
[Protocol 12-279]
Chaft, Jamie, MD
A Phase I Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancer
[Protocol 11-170]
Paik, Paul, MD
A Phase I Study of BMS-936558 with Combination Chemotherapy for Patients with Previously Untreated Stage IIIB or IV Non-Small Cell Lung Cancer
[Protocol 11-189]
Rizvi, Naiyer, MD
A Phase I Study of BMS-986015 plus BMS-936558 in Patients with Advanced Solid Tumors
[Protocol 12-224]
Segal, Neil, MD, PhD
A Phase I Study of BMS-986015 with Ipilimumab in Patients with Advanced Non-Small Cell Lung Cancer, Prostate Cancer, or Melanoma
[Protocol 12-283]
Rizvi, Naiyer, MD
A Phase I Study of GL-ONC1 for Treating Malignant Pleural Effusion
[Protocol 12-169]
Rusch, Valerie, MD
A Phase I Study of LDK378 in Adults with Non-Small Cell Lung Cancers Containing an ALK Gene Fusion
[Protocol 11-055]
Riely, Gregory, MD, PhD
A Phase I/II Study of Crizotinib and STA-9090 in ALK-Positive Lung Cancers
[Protocol 12-015]
Riely, Gregory, MD, PhD
A Phase I/II Study of the ALK Inhibitor CH5424802 in Patients with ALK-Rearranged Non-Small Cell Lung Cancer
[Protocol 12-113]
Riely, Gregory, MD, PhD
A Phase I/II Trial of AUY-922 in Patients with Lung Adenocarcinoma with Acquired Resistance to Erlotinib or Gefitinib
[Protocol 11-015]
Riely, Gregory, MD, PhD
A Phase IB Study of BKM120 plus MEK162 in Select Patients with Advanced Solid Tumors
[Protocol 11-117]
Gounder, Mrinal, MD
A Phase IB/II Study of IPI-504 plus Everolimus in Patients with KRAS-Mutant Non-Small Cell Lung Cancer
[Protocol 11-114]
Riely, Gregory, MD, PhD
A Phase II Study Evaluating Manuka Honey to Reduce Chemoradiation-Associated Esophagitis Pain during Lung Cancer Treatment
[Protocol 12-111]
Rimner, Andreas, MD
A Phase II Study of BKM120 in Patients with Metastatic Non-Small Cell Lung Cancer
[Protocol 11-157]
Paik, Paul, MD
A Phase II Study of BMS-936558 in Patients with Previously Treated Advanced Squamous Cell Lung Cancer
[Protocol 12-284]
Rizvi, Naiyer, MD
A Phase II Study of Bortezomib in Patients with KRAS-Mutant Non-Small Cell Lung Cancer
[Protocol 12-222]
Riely, Gregory, MD, PhD
A Phase II Study of Cabozantinib in Patients with Advanced Non-Small Cell Lung Cancer
[Protocol 12-097]
Rizvi, Naiyer, MD
A Phase II Study of Dasatinib in Patients with Advanced Non-Small Cell Lung Cancers with DDR2 or Inactivating BRAF Mutations
[Protocol 12-163]
Paik, Paul, MD
A Phase II Study of GSK2118436 in Patients with Advanced Non-Small Cell Lung Cancer and BRAF Mutations
[Protocol 11-023]
Riely, Gregory, MD, PhD
A Phase II Study of Neoadjuvant Pemetrexed Plus Cisplatin for Patients with Resectable Non-Squamous Non-Small Cell Lung Cancer with "Switch Chemotherapy Alternative" in Non-Responders (NEOSCAN)
[Protocol 11-106]
Chaft, Jamie, MD
A Phase III Study of BMS-936558 versus Docetaxel in Patients with Previously Treated Metastatic Non-Squamous Non-Small Cell Lung Cancer
[Protocol 12-252]
Rizvi, Naiyer, MD
A Phase III Study of Sublobar Resection versus Stereotactic Body Radiation Therapy in High-Risk Patients with Stage I Non-Small Cell Lung Cancer
[Protocol 13-003]
Gelblum, Daphna, MD
Use of High-Resolution Structural MRI to Assess Changes in Brain Structure Related to Chemotherapy in Patients with Non-Small Cell Lung Cancer: A Prospective Study
[Protocol 11-145]
Root, James, PhD