Soft Tissue Sarcoma: Our Clinical Trials

We lead a number of clinical trials to improve on current standards for treatment and to enhance quality of life. Clinical trials are research studies that evaluate the safety and effectiveness of new ways to diagnose and treat soft tissue sarcoma. These studies can also help doctors compare the effectiveness of prevention strategies or other aspects of your care.

Memorial Sloan Kettering’s clinical trials for soft tissue sarcomas are listed below. There may be additional trials that are appropriate for your cancer. We recommend that you consult with your physician, who can inquire on your behalf as to whether a trial is appropriate for you.

Showing 19 trials
Title Investigatorsort icon
A Phase II Study of Whole-Lung IMRT in Children and Adults with Synovial Sarcoma that Spread to the Lungs
[Protocol 14-075]
Wolden, Suzanne, MD
A Phase II Study of Cyclophosphamide, Topotecan, and Bevacizumab in Patients with Relapsed or Refractory Ewing's Sarcoma and Neuroblastoma
Newly Diagnosed & Relapsed/Refractory
[Protocol 11-183]
Trippett, Tanya, MD
A Phase III Study of Doxorubicin Alone or in Combination with TH-302 in Patients with Locally Advanced Inoperable or Metastatic Soft-Tissue Sarcoma
[Protocol 11-203]
Tap, William, MD
A Phase I Study of PLX3397 in Patients with Advanced Solid Tumors
[Protocol 12-156]
Tap, William, MD
A Phase Ib/II Study of Gemcitabine and Docetaxel Plus Pazopanib for the Neoadjuvant (Presurgical) Treatment of Soft-Tissue Sarcoma
[Protocol 11-104]
Tap, William, MD
A Phase I Study of Humanized 3F8 plus Interleukin-2 in Patients with High-Risk Neuroblastoma and GD2-Positive Tumors
Relapsed/Refractory
[Protocol 12-116]
Roberts, Stephen, MD
A Phase II Study of Irinotecan and Temozolomide in Combination with Existing High-Dose Chemotherapy for Patients Newly Diagnosed with Ewing Sarcoma
[Protocol 13-068]
Magnan, Heather, MD
A Phase I/II Study of Sunitinib in Young Patients with Advanced Gastrointestinal Stromal Tumors
Newly Diagnosed & Relapsed/Refractory
[Protocol 12-226]
Magnan, Heather, MD
A Pilot Trial of Irinotecan, Temozolomide, and Bevacizumab plus High-Dose Chemotherapy for Newly Diagnosed Patients with Desmoplastic Small Round Cell Tumor
[Protocol 10-091]
Magnan, Heather, MD
A Phase 1B/II Study of GDC-0449 Plus RO4929097 in Advanced/Metastatic Sarcomas
[Protocol 10-049]
Gounder, Mrinal, MD
A Phase I Study Assessing the Effects of Food and Formulation on the Processing of KPT-330 in Patients with Sarcoma
[Protocol 13-145]
Gounder, Mrinal, MD
A Phase III Study of Sorafenib versus Placebo in Patients with Desmoid Tumors
[Protocol 14-015]
Gounder, Mrinal, MD
A Phase II Study of MLN8237 in Advanced or Metastatic Sarcoma
[Protocol 12-194]
Dickson, Mark, MD
A Phase I Study of SAR405838 in Patients with Advanced Cancer
[Protocol 13-093]
Dickson, Mark, MD
A Pilot Study of Genetically Engineered NY-ESO-1-Specific T Cells in Children and Adults with Persistent Synovial Sarcoma
[Protocol 13-236]
D'Angelo, Sandra, MD
A Phase III Study of Preoperative Radiotherapy plus Surgery versus Surgery Alone for Patients with Retroperitoneal Sarcoma
[Protocol 14-051]
Crago, Aimee, MD
A Phase Ib/II Study of MEK162 with Imatinib in Patients with Untreated Advanced Gastrointestinal Stromal Tumor
[Protocol 13-162]
Chi, Ping, MD, PhD
A Phase I Study of Dasatinib and Ipilimumab for Patients with Advanced GIST or Other Sarcomas
[Protocol 12-083]
Carvajal, Richard, MD
A Phase I Study of Humanized 3F8 Monoclonal Antibody in Patients with High-Risk Neuroblastoma and GD2-Positive Tumors
[Protocol 11-009]
Basu, Ellen, MD, PhD