Uterine Sarcoma: Diagnosis & Treatment at Memorial Sloan Kettering

At Memorial Sloan Kettering, every woman with uterine sarcoma is cared for by a multidisciplinary team of experts that includes specialists in medical oncology, gynecologic oncology, surgery, radiology, radiation oncology, and pathology. The team is highly experienced in diagnosing and treating women with uterine sarcoma.

We use sophisticated imaging, laboratory, and tissue-sampling tests to confirm your diagnosis and identify the characteristics of the tumor. Because uterine sarcomas are so rare and each sarcoma type behaves differently, one of our highly trained pathologists who specialize in sarcoma will review the tumor tissue to make a definitive diagnosis.

Memorial Sloan Kettering surgeons are some of the most experienced in the world in approaching the removal of uterine sarcomas, and can in many cases offer minimally invasive procedures that reduce the side effects and time involved in recovery. Surgery alone may be curative if no cancer cells have spread beyond the uterus.

We also have medical oncologists who are experts in diagnosing and treating uterine sarcomas. The management of these rare tumors is optimized under the guidance of physicians who have extensive experience with them and understand their nuances and variability in behavior.

At every step, our specialists will work with you to determine the best treatment approach, taking into consideration everything from the specific type of sarcoma to the stage of the cancer and the condition of your overall health.

We also have an active research and clinical trials program and are working to develop more-effective therapies for uterine sarcomas.

For example, our team led the way in demonstrating the efficacy of a novel chemotherapy regimen (gemcitabine and docetaxel) to treat leiomyosarcoma that has metastasized (spread) to other parts of the body and cannot be removed surgically. This treatment regimen is now considered a standard treatment for uterine leiomyosarcoma, recommended by National Comprehensive Cancer Network (NCCN) guidelines.

Learn about how we diagnose and treat uterine sarcoma.