Guenther Koehne, MD, PhD

I am a physician-scientist whose clinical focus is treating patients with hematologic malignancies, and I have particular expertise in allogeneic (donor-derived) hematopoietic stem cell transplantation for patients with leukemia, lymphoma, myelodysplastic syndrome, and multiple myeloma. At Memorial Sloan-Kettering Cancer Center, we are pioneering a new type of stem cell transplantation in which we remove a specific subset of cells (T cells) from the donor’s stem cells before the transplant; this significantly reduces the so-called graft-versus-host reactions. As the principle investigator, I am leading clinical trials to study the effectiveness of T cell-depleted transplants from related and unrelated donors in patients with high-risk multiple myeloma.