Jorge S. Reis-Filho, MD, PhD, FRCPath

Our laboratory in the Human Oncology and Pathogenesis Program also focuses on the impact of intra-tumor genetic heterogeneity on the biology and clinical behavior of breast cancers, and on the development of diagnostic, prognostic, and predictive biomarkers. We are currently investigating whether circulating DNA and/or circulating tumor cells can be used to define the constellation of mutations found in primary or metastatic breast cancers and whether the genetic analyses of these biological materials would complement the analysis of the primary tumor for clinical decision-making.

Memorial Sloan-Kettering Cancer Center provides an optimal environment for me to pursue these research aims, given its collegial and collaborative environment, the well-characterized institutional collections of rare tumor types, and state-of-the-art research facilities.

Over the past seven years, I have lectured at various national and international conferences, and mentored PhD and MD students. I am the recipient of the 2007 CL Oakley Lectureship by the Pathological Society of Great Britain and Ireland, the British Association for Cancer Research 2007 Translational Research Award, the 2010 Ramzi Cotran Young Investigator Award by the United States and Canadian Academy of Pathology, and the 2010 Future Leaders Prize by Cancer Research UK. I am the youngest-ever Fellow of The Royal College of Pathologists to have become a member by published works. I am the international editor of Advances in Anatomical Pathology, an associate editor of The Journal of Pathology and BMC Cancer, a member of the scientific advisory board of Science Translational Medicine, and a member of the editorial board of Laboratory Investigation and Modern Pathology.