Shakeel Modak, MD

I am a pediatric oncologist who specializes in the treatment of children and young adults with neuroblastoma and other solid tumors, such as desmoplastic small round cell tumors. These are challenging cancers to treat. By caring for patients and conducting research, I hope to be able make an impact and improve the lives of people diagnosed with these diseases.

Our multidisciplinary team of healthcare professionals discusses each patient's case in order to put together an individualized treatment plan. Memorial Sloan-Kettering treats a large number of patients with neuroblastoma, and this volume has afforded us a wealth of knowledge and depth of expertise that benefit all patients. I am also inspired by the parents of my patients, who work tirelessly to support each other and to raise funds for research. They are vital members of our team.

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With my colleagues, I translate laboratory research into new immunologic therapies that can target these tumors. We are evaluating radiolabeled monoclonal antibody treatments in combination with cell-based therapies that may enhance their effectiveness. Our research has defined the standards of care used to treat neuroblastoma today.

I also expertly served as chair for the department’s quality assessment committee for many years and have overseen the development and implementation of dozens of strategies, changes, and enhancements to improve patient safety and satisfaction.

In addition to caring for patients and conducting research, I teach and mentor fellows. I am able to provide them with a unique viewpoint on rare diseases that are difficult to find at other institutions. It is gratifying for me to see them make their own contributions to our field.

Location

New York City

Appointments for New Patients

212-639-5954

Phone

212-639-7623

Clinical Expertise

Pediatric Hematology-Oncology; Immunotherapy; Neuroblastoma

Languages Spoken

English

Education

MD, T.N. Medical College, Bombay University (India)

Residencies

B.Y.L. Nair Charitable Hospital (Bombay, India); Birmingham Children’s Hospital (UK); Blank Children’s Hospital (Des Moines, Iowa)

Fellowships

Royal Marsden Hospital (Sutton, UK); NewYork-Presbyterian Hospital; Memorial Sloan-Kettering Cancer Center

Board Certifications

Pediatrics; Hematology-Oncology

See My Colleagues in:

Department of Pediatrics

Clinical Trials Led by Shakeel Modak

A Phase I Study of Anti-GD2 3F8 Antibody and Allogeneic Natural Killer Cells for High-Risk Neuroblastoma

A Phase I Study of Intraperitoneal Radioimmunotherapy with 131I-8H9 for Patients with Desmoplastic Small Round Cell Tumors and Other Solid Peritoneal Tumors

A Phase II Study of Bevacizumab, Irinotecan, and Temozolomide for Relapsed or Refractory Neuroblastoma

A Pilot Phase II Study of Targeted Radiotherapy with 131I-MIBG and Arsenic Trioxide in Patients with Resistant Neuroblastoma or Malignant Chromaffin Cell Tumors

Clinical Trials Co-Investigated by Shakeel Modak

Molecular Characterization of Neuroblastic Tumors and Clinical Outcome

Publications by Shakeel Modak

Visit PubMed for full listing of Shakeel Modak journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Topics Recommended by Shakeel Modak

Pediatric Cancer Care

antibody (AN-tee-BAH-dee)

A protein made by plasma cells (a type of white blood cell) in response to an antigen (a substance that causes the body to make a specific immune response). Each antibody can bind to only one specific antigen. The purpose of this binding is to help destroy the antigen. Some antibodies destroy antigens directly. Others make it easier for white blood cells to destroy the antigen.