Health Care Professional Information
Clinical Summary
Music as therapy has been used since ancient times. It emerged as a formal discipline in the United States in the late 1940s. Currently, there are over 5,000 music therapists working in clinical settings throughout the country. Patients listen to or perform music under the guidance of a professionally trained music therapist. Music can promote relaxation and provide distraction from pain. It has been used to reduce postoperative pain (13) and to help alleviate anxiety and stress (1) (2). Preliminary data also suggest that music may help in improving social and emotional aspects in patients with Alzheimer's disease (3) (4) (5) and improved quality of life in patients with dementia (6) and stroke (7).
Music therapy may also help alleviate symptoms associated with cancer and its treatments. In one study, music reduced mood disturbance in cancer patients undergoing autologous stem cell transplantation, a procedure known to cause significant psychological distress (10). Other data indicate that music alleviates pain (15) and anxiety in breast cancer patients (14), in those receiving chemotherapy (16) and radiation therapy (11), and improves the quality of life in people with terminal cancer (12). Music also reduces pain and anxiety, and increases comfort in hospitalized children with cancer (9) (17). Women undergoing colposcopy reported reduced anxiety and pain perception after listening to slow-rhythm music (8).
Conclusions from systematic reviews, however, question the clinical significance of music therapy for treating pain (18), and also point to the poor methodology in several music therapy trials (19).
Because music therapy is noninvasive and free of side effects, it is being integrated into the standard care in major cancer hospitals to help relieve pain and physical and psychological discomfort.
Purported Uses
- Cancer-related symptoms
- Mood disturbance
- Pain
- Stress
Literature Summary and Critique
Bradt J, Dileo C, Grocke D, Magill L. Music interventions for improving psychological and physical outcomes in cancer patients. Cochrane Database Syst Rev. 2011 Aug 10;(8):CD006911.
This systematic review involving 30 clinical trials and 1891 subjects was conducted to compare the effects of music therapy or music
medicine interventions and standard care with standard care alone, or standard care and other interventions in improving psychological and physical outcomes in patients with cancer. Databases used for the review included the Cochrane Central Register of Controlled Trials (CENTRAL) Cochrane Library 2010, Issue 10), MEDLINE, EMBASE, CINAHL, PsycINFO, LILACS, Science Citation Index, CancerLit,
www.musictherapyworld.net, CAIRSS, Proquest Digital Dissertations, ClinicalTrials.gov, Current Controlled Trials, and the National Research Register.
Results indicate beneficial effects of music on anxiety, pain, mood, and quality of life in cancer patients. However, the authors point to the lack of a robust study design in several trials included in the review. Additional studies with strong methodology are needed to establish use of music therapy.
Cassileth BR, et al. Music therapy for mood disturbance during hospitalization for autologous stem cell transplantation: a randomized controlled trial. Cancer 2003;98(12):2723-9.
This study involved 69 patients with hematologic malignancy scheduled to undergo high-dose therapy with autologous stem cell transplantation (HDT/ASCT), a procedure that causes significant psychological distress. Patients were randomized to receive music therapy given by trained music therapists or standard care. Patients who received music therapy reported less mood disturbance compared to the control group. Researchers suggest that music therapy can be used as an effective intervention to reduce mood disturbance in patients undergoing HDT/ASCT.
Hilliard RE. The effects of music therapy on the quality and length of life of people diagnosed with terminal cancer. J Music Ther 2003;40(2):113-37.
Eighty patients with terminal cancer were randomly assigned in this study to receive music therapy or routine care. All participants received at least two visits and quality of life assessments. Patients who received music therapy experienced increased quality of life compared to those who received only routine care. Although there were no significant differences between the two groups in physical functioning or length of life, music therapy improved the quality of life in patients with terminal cancer.
References
- Salamon E, et al. The effects of auditory perception and musical preference on anxiety in naive human subjects. Med Sci Monit 2003; 9(9):CR396-CR399.
- Allen K, et al. Normalization of hypertensive responses during ambulatory surgical stress by perioperative music. Psychosom Med 2001; 63(3):487-492.
- Brotons M and Marti P. Music therapy with Alzheimer's patients and their family caregivers: a pilot project. J Music Ther 2003; 40(2):138-150.
- Quoniam N, et al. Implicit and explicit emotional memory for melodies in Alzheimer's disease and depression. Ann N Y Acad Sci 2003; 999:381-384.
- Suzuki M et al. Behavioral and endocrinological evaluation of music therapy for elderly patients with dementia. Nurs Health Sci 2004; 6(1):11-18.
- Gotell E, et al. Influence of caregiver singing and background music on posture, movement, and sensory awareness in dementia care. Int Psychogeriatr 2003; 15(4):411-430.
- Schauer M and Mauritz KH. Musical motor feedback (MMF) in walking hemiparetic stroke patients: randomized trials of gait improvement. Clin Rehabil 2003; 17(7):713-722.
- Chan YM, et al. The use of music to reduce anxiety for patients undergoing colposcopy: a randomized trial. Gynecol Oncol 2003; 91(1):213-217.
- Barrera ME, et al. The effects of interactive music therapy on hospitalized children with cancer: a pilot study. Psychooncology 2002; 11(5):379-388.
- Cassileth BR, et al. Music therapy for mood disturbance during hospitalization for autologous stem cell transplantation: a randomized controlled trial. Cancer 2003; 98(12):2723-2729.
- Smith M, et al. Music as a therapeutic intervention for anxiety in patients receiving radiation therapy. Oncol Nurs Forum 2001; 28(5):855-862.
- Hilliard RE. The effects of music therapy on the quality and length of life of people diagnosed with terminal cancer. J Music Ther 2003; 40(2):113-137.
- Good M, et al. Relaxation and music reduce pain after gynecologic surgery. Pain Manag Nurs 2002;3(2):61-70.
- Bulfone T, Quattrin R, Zanotti R, et al. Effectiveness of music therapy for anxiety reduction in women with breast cancer in chemotherapy treatment. Holist Nurs Pract. 2009;23(4):238-42.
- Li XM, Yan H, Zhou KN, et al. Effects of music therapy on pain among female breast cancer patients after radical mastectomy: results from a randomized controlled trial. Breast Cancer Res Treat. 2011 May 3. [Epub ahead of print]
- Lin MF, Hsieh YJ, Hsu YY, Fetzer S, Hsu MC. A randomised controlled trial of the effect of music therapy and verbal relaxation on chemotherapy-induced anxiety. J Clin Nurs. 2011 Apr;20(7-8):988-99.
- Nguyen TN, Nilsson S, Hellström AL, Bengtson A. Music therapy to reduce pain and anxiety in children with cancer undergoing lumbar puncture: a randomized clinical trial. J Pediatr Oncol Nurs. 2010 May-Jun;27(3):146-55.
-
Cepeda MS, Carr DB, Lau J, Alvarez H.
Music for pain relief. Cochrane Database Syst Rev. 2006 Apr 19;(2):CD004843.
-
Consumer Information
How It Works
Bottom Line: Music can promote relaxation and distraction from pain associated with many illnesses.
Music therapy has emerged as a formal discipline in the United States in the 1940s. Currently, there are over 5,000 trained therapists working throughout the country. Patients listen to or perform music under the guidance of a professionally trained music therapist. Studies have shown that music reduces anxiety, stress and pain after surgery. Music is thought to reduce blood pressure in the listeners. It improves coordination in stroke and Parkinson's disease patients. Music helps improve social and emotional aspects in patients with Alzheimer's disease and improved quality of life in patients with dementia. A recent study has shown that music is effective in improving depressive symptoms. Music has clinically significant benefits for premature infants in intensive care units. It also helps to change behaviors in children with autism and to reduce anxiety and increase comfort in hospitalized children with cancer. Music therapy can reduce mood disturbance in cancer patients undergoing stem cell transplantation. It also reduced anxiety in patients receiving radiation therapy and improved the quality of life in people with terminal cancer.
Because music therapy is noninvasive and free of side effects, it is being added into the standard care in major cancer hospitals.
Purported Uses
- Pain
Several clinical trials have shown that music therapy can help to reduce pain.
- Stress
This use is supported by clinical trials.
- Cancer-related symptoms
A few studies support this use.
Research Evidence
Cancer
In one study, blood cancer patients receiving music therapy during autologous stem-cell transplantation had less mood disturbance when compared to those in the control group.
Another study showed that terminal cancer patients who received music therapy experienced improved quality of life compared to the control group.
A systematic review of music therapy trials showed that many studies are poorly designed with small sample size leading to biased reporting of results.
Last updated: January 19, 2012
anxiety (ang-ZY-eh-tee)
Feelings of fear, dread, and uneasiness that may occur as a reaction to stress. A person with anxiety may sweat, feel restless and tense, and have a rapid heart beat. Extreme anxiety that happens often over time may be a sign of an anxiety disorder.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
autologous (aw-TAH-luh-gus)
Taken from an individual's own tissues, cells, or DNA.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
autologous stem cell transplantation (aw-TAH-luh-gus ... tranz-plan-TAY-shun)
A procedure in which blood-forming stem cells (cells from which all blood cells develop) are removed, stored, and later given back to the same person.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
blood (blud)
A tissue with red blood cells, white blood cells, platelets, and other substances suspended in fluid called plasma. Blood takes oxygen and nutrients to the tissues, and carries away wastes.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
breast (brest)
Glandular organ located on the chest. The breast is made up of connective tissue, fat, and breast tissue that contains the glands that can make milk. Also called mammary gland.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
cancer (KAN-ser)
A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
cell (sel)
The individual unit that makes up the tissues of the body. All living things are made up of one or more cells.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
chemotherapy (KEE-moh-THAYR-uh-pee)
Treatment with drugs that kill cancer cells.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
clinical (KLIH-nih-kul)
Having to do with the examination and treatment of patients.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
colposcopy (kol-POS-koh-pee)
Examination of the vagina and cervix using a lighted magnifying instrument called a colposcope.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
control group (kun-TROLE groop)
In a clinical trial, the group that does not receive the new treatment being studied. This group is compared to the group that receives the new treatment, to see if the new treatment works.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
dementia (deh-MEN-shuh)
A condition in which a person loses the ability to think, remember, learn, make decisions, and solve problems. Symptoms may also include personality changes and emotional problems. There are many causes of dementia, including Alzheimer disease, brain cancer, and brain injury. Dementia usually gets worse over time.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
distress (dih-STRESS)
Extreme mental or physical pain or suffering.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
intervention (IN-ter-VEN-shun)
In medicine, a treatment or action taken to prevent or treat disease, or improve health in other ways.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
malignancy (muh-LIG-nun-see)
A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Malignant cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of malignancy. Carcinoma is a malignancy that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a malignancy that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a malignancy that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are malignancies that begin in the cells of the immune system. Central nervous system cancers are malignancies that begin in the tissues of the brain and spinal cord. Also called cancer.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
medicine (MEH-dih-sin)
Refers to the practices and procedures used for the prevention, treatment, or relief of symptoms of a diseases or abnormal conditions. This term may also refer to a legal drug used for the same purpose.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
methodology (MEH-thuh-DAH-loh-jee)
In medicine, the rules and procedures for doing research and evaluating results.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
music therapy (MYOO-sik THAYR-uh-pee)
Treatment that uses music to help relieve pain or stress and promote well-being. It is being studied in the treatment of several cancer-related problems and other conditions.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
noninvasive (NON-in-VAY-siv)
In medicine, it describes a procedure that does not require inserting an instrument through the skin or into a body opening. In cancer, it describes disease that has not spread outside the tissue in which it began.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
psychological (SY-koh-LAH-jih-kul)
Having to do with how the mind works and how thoughts and feelings affect behavior.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
quality of life (KWAH-lih-tee ... life)
The overall enjoyment of life. Many clinical trials assess the effects of cancer and its treatment on the quality of life. These studies measure aspects of an individual’s sense of well-being and ability to carry out various activities.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
radiation (RAY-dee-AY-shun)
Energy released in the form of particle or electromagnetic waves. Common sources of radiation include radon gas, cosmic rays from outer space, medical x-rays, and energy given off by a radioisotope (unstable form of a chemical element that releases radiation as it breaks down and becomes more stable).
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
radiation therapy (RAY-dee-AY-shun THAYR-uh-pee)
The use of high-energy radiation from x-rays, gamma rays, neutrons, protons, and other sources to kill cancer cells and shrink tumors. Radiation may come from a machine outside the body (external-beam radiation therapy), or it may come from radioactive material placed in the body near cancer cells (internal radiation therapy). Systemic radiation therapy uses a radioactive substance, such as a radiolabeled monoclonal antibody, that travels in the blood to tissues throughout the body. Also called irradiation and radiotherapy.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
randomized
Describes an experiment or clinical trial in which animal or human subjects are assigned by chance to separate groups that compare different treatments.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
significant (sig-NIH-fih-kunt)
In statistics, describes a mathematical measure of difference between groups. The difference is said to be significant if it is greater than what might be expected to happen by chance alone. Also called statistically significant.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
stem cell (stem sel)
A cell from which other types of cells develop. For example, blood cells develop from blood-forming stem cells.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
stress (stres)
The response of the body to physical, mental, or emotional pressure. This may make a person feel frustrated, angry, or anxious, and may cause unhealthy chemical changes in the body. Untreated, long-term stress may lead to many types of mental and physical health problems.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
stroke (stroke)
In medicine, a loss of blood flow to part of the brain, which damages brain tissue. Strokes are caused by blood clots and broken blood vessels in the brain. Symptoms include dizziness, numbness, weakness on one side of the body, and problems with talking, writing, or understanding language. The risk of stroke is increased by high blood pressure, older age, smoking, diabetes, high cholesterol, heart disease, atherosclerosis (a build-up of fatty material and plaque inside the coronary arteries), and a family history of stroke.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
surgery (SER-juh-ree)
A procedure to remove or repair a part of the body or to find out whether disease is present. An operation.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
therapy (THAYR-uh-pee)
Treatment.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
transplantation (tranz-plan-TAY-shun)
A surgical procedure in which tissue or an organ is transferred from one area of a person’s body to another area, or from one person (the donor) to another person (the recipient).
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)