Protocol
09-094
Full Title
Does Maitake Mushroom Extract Enhance Hematopoiesis in Myelodysplastic Patients? A Phase II Trial
Purpose
In people with myelodysplastic syndrome, the bone marrow does not work normally. As a result, they may have abnormally low levels of functioning blood cells (such as red blood cells, white blood cells, and platelets).
Laboratory studies show that maitake mushroom extract can reduce the growth of cancer in animals. Maitake extract does not kill cancer cells directly. It is believed to work through the immune system.
Studies have shown that maitake extract can enhance immune function. Researchers are conducting this study to see whether maitake mushroom extract improves neutrophil count and function in patients with myelodysplastic syndrome. Neutrophils are white blood cells that help to fight infection. Maitake extract comes in a small bottle with a liquid medicine dropper.
Investigator
Wesa, Kathleen, MD
Eligibility
To be eligible for this study, patients must meet several criteria, including but not limited to the following:
- Have low-risk or intermediate-risk myelodysplastic syndrome.
- Neutrophil counts must be over 500 and platelet counts over 50,000.
- No mushroom allergy.
- No history of acute myelogenous leukemia (AML) or stem cell transplant.
- Age 18 or older.
For more information about this study and to inquire about eligibility, please contact Research Study Assistant Allison Hirsch at 646-888-0810, Clinical Research Coordinator Gria Jacobs at 646-888-0804, or Principal Investigator Dr. Kathleen Wesa at 646-888-0839.
Disease(s)
Myelodysplastic Syndrome
