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Atovaquone and Proguanil (a TOE va kwone & pro GWA nil)

Pediatric Medication

Brand Names: U.S.

Malarone®

Brand Names: Canada

Malarone®; Malarone® Pediatric

Warning

  • Sometimes drugs are not safe when your child takes them with other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your child’s doctor about all the drugs your child takes.

What is this drug used for?

  • It is used to treat or prevent malaria.

Is it safe for my child to take this drug?

  • Not if your child has an allergy to atovaquone, proguanil, or any other part of this drug.
  • Be sure to let the doctor know if your child has any allergies or side effects to drugs, foods, or dyes. Make sure to tell about the allergy and what signs your child had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • Not if your child is using this drug to stop malaria and has very bad kidney disease.

What are some things I need to know or do while my child takes this drug?

  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • If your child has kidney disease, talk with the doctor.
  • If your child has liver disease, talk with the doctor.
  • Other measures are needed along with this drug including using screens, bed netting, insect repellent (10% to 35% DEET), and permethrin spray on clothing and nets. Avoid spraying most insect repellents on children. Lower evening and night-time outdoor activity.
  • Check all drugs your child is taking with your child’s doctor. This drug may not mix well with some other drugs.

What are some side effects that I need to call my child’s doctor about right away?

  • If any of this news causes you to be worried, any of the unwanted side effects happen, or if your child is not better after taking this drug.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
  • If your child shows signs of a very bad reaction, call your child’s doctor or the ER right away. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; swelling of face, lips, tongue, or throat; or if your child is not acting normal.
  • If your child has a fever that happens while in or after coming back from the malaria area.
  • If your child has a very bad upset stomach or is throwing up.
  • If your child has very loose stools (diarrhea).
  • If your child gets a rash.
  • If your child’s health problem does not get better or if you think your child’s health problem is worse.

What are some other side effects of this drug?

  • To lower the chance of feeling dizzy or passing out, have your child get up slowly over a few minutes when sitting or lying down. Have your child be extra careful climbing stairs.
  • Headache.
  • Belly pain.
  • Upset stomach or throwing up. Many small meals and good mouth care may help. Older children may suck hard, sugar-free candy.
  • Loose stools (diarrhea).

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read and follow the dosing on the label closely.
  • Start this drug before travel to the high risk place. Keep using after leaving.
  • To gain the most benefit, do not miss giving your child doses.
  • Give as you have been told to help prevent malaria.
  • Give this drug at the same time of day.
  • Give this drug with food.
  • If your child throws up within 1 hour of taking this drug, give 1 more dose.
  • You may crush the tablet and mix it with milk.

What do I do if my child misses a dose?

  • Give a missed dose as soon as you think about it.
  • If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
  • Do not give 2 doses or extra doses.
  • Do not change the dose or stop your child’s drug. Talk with your child’s doctor.

How do I store and/or throw out this drug?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date

2012-03-15

Copyright

Copyright © 2014 Clinical Drug Information, LLC and Lexi-Comp, Inc.