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Buprenorphine and Naloxone (byoo pre NOR feen & nal OKS one)

Adult Medication

Brand Names: U.S.

Bunavail; Suboxone; Zubsolv

Brand Names: Canada

Suboxone

What is this drug used for?

  • It is used to treat drug addiction and withdrawal.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to buprenorphine, naloxone, or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have liver disease.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell dentists, surgeons, and other doctors that you use this drug.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly over a few minutes when sitting or lying down. Be careful climbing stairs.
  • Have your blood work checked often. Talk with your doctor.
  • This drug may be habit-forming with long-term use.
  • Do not stop taking this drug all of a sudden without calling your doctor. You may have a greater risk of signs of withdrawal. If you need to stop this drug, you will want to slowly stop it as ordered by your doctor.
  • Do not switch between different forms of this drug without first talking with the doctor.
  • Talk with your doctor before you use other drugs and natural products that slow your actions.
  • Avoid drinking alcohol.
  • Even one dose of this drug may be deadly if it is taken by accident. Children are at higher risk. If this drug is taken by accident, get medical help right away.
  • If you are 65 or older, use this drug with care. You could have more side effects.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  • Long-term use of this drug during pregnancy may cause dependence in the unborn baby or newborn. Talk with the doctor.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad dizziness or passing out.
  • Trouble breathing, slow breathing, or shallow breathing.
  • Feeling very sleepy.
  • Change in thinking clearly and with logic.
  • Very hard stools (constipation).
  • Change in eyesight.
  • Feeling very tired or weak.
  • Feeling nervous and excitable.
  • Change in balance.
  • Mood changes.
  • Anxiety.
  • Extra muscle action or slow movement.
  • Slurred speech.
  • Very bad and sometimes deadly liver problems have happened with this drug. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

All products:

  • Dizziness.
  • Feeling sleepy.
  • Upset stomach or throwing up.
  • Hard stools (constipation).
  • Headache.
  • Belly pain.
  • Not able to sleep.
  • Feeling tired or weak.
  • Sweating a lot.
  • Flushing.
Under the tongue (sublingual) film:
  • Burning.
  • Numbness or tingling in the mouth.
  • Pain where it was placed.
  • Redness.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.

All products:

  • To gain the most benefit, do not miss doses.
  • Take this drug at the same time of day.
  • Do not chew or swallow.
  • Do not eat, drink, smoke, or talk while this drug is melting.
  • Take by mouth only. Very bad and sometimes deadly side effects may happen if this drug is injected.

All film products:

  • Open right before use.
  • Be sure your hands are dry before you touch this drug.
  • Do not cut or tear this drug. Do not touch the film with your tongue or finger once it has been placed.
Under the tongue (sublingual) film:
  • Wet mouth with water.
  • Place film under your tongue.
  • If using 2 films, place on opposite sides. Try not to let films touch.
  • If using 3 films, place the third film under the tongue after the first 2 films have melted.

Cheek film:

  • Wet the inside of your cheek with your tongue or water.
  • Place the film inside the mouth on a wet cheek. Hold for 5 seconds so it sticks to the cheek. Let it melt.
  • Place the side of the film with the writing against the inside of the cheek.
  • If using 2 films, place on opposite sides. If using many films, do not place more than 2 films on the inside of 1 cheek at a time.
Under the tongue (sublingual) tablet:
  • Place on the tongue and let melt.
  • If your doctor tells you to use more than 1 tablet at a time, ask your doctor how to take them.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
  • If you are not sure what to do if you miss a dose, call your doctor.

How do I store and/or throw out this drug?

All products:

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

All film products:

  • Do not freeze.
  • Store in foil pouch until ready for use.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date

2014-06-27

Copyright

Copyright © 2014 Clinical Drug Information, LLC and Lexi-Comp, Inc.