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Capecitabine (ka pe SITE a been)

Brand Names: U.S.

Xeloda

Brand Names: Canada

Teva-Capecitabine; Xeloda

Warning

  • Very bad and sometimes deadly bleeding problems have happened in people taking this drug with warfarin. This has happened within a few days after this drug was started and up to 1 month after this drug was stopped. Your risk for bleeding problems is higher if you are older than 60 or have cancer. If you are taking a blood thinner, you must have your blood work checked often. Talk with your doctor.

What is this drug used for?

  • It is used to treat colorectal cancer.
  • It is used to treat breast cancer.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to capecitabine, fluorouracil (5-FU), or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have a dihydropyrimidine dehydrogenase (DPD) deficiency or kidney disease.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell dentists, surgeons, and other doctors that you use this drug.
  • You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
  • You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
  • This drug may raise the chance of a very bad and sometimes deadly heart problem. Talk with your doctor.
  • It is common to have loose stools (diarrhea) when taking this drug. Some cases of loose stools may cause fluid loss and kidney problems that can sometimes be deadly. Call your doctor right away if you have loose stools that do not go away or if you have very loose stools. Do not try to treat loose stools without first checking with your doctor.
  • If you have upset stomach, throwing up, loose stools (diarrhea), or are not hungry, talk with your doctor. There may be ways to lower these side effects.
  • If the tablet is crushed or broken, do not touch the contents. If you do touch the contents or get it in your eyes, wash hands or eyes right away.
  • Have your blood work checked often. Talk with your doctor.
  • Talk with your doctor before getting any vaccines. Use with this drug may either raise the chance of an infection or make the vaccine not work as well.
  • If you are over the age of 60, use this drug with care. You could have more side effects.
  • This drug may cause harm to the unborn baby if you take it while you are pregnant.
  • Use birth control that you can trust to prevent pregnancy while taking this drug.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
  • Signs of fluid and electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, very bad dizziness or passing out, fast heartbeat, more thirst, seizures, feeling very tired or weak, not hungry, unable to pass urine or change in the amount of urine produced, dry mouth, dry eyes, or very bad upset stomach or throwing up.
  • Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
  • Shortness of breath.
  • Chest pain or pressure.
  • A heartbeat that does not feel normal.
  • Very upset stomach or throwing up.
  • Very loose stools (diarrhea).
  • Numbness or tingling in your hands or feet.
  • Any bruising or bleeding.
  • Very bad skin irritation.
  • Very bad mouth irritation.
  • Swelling in hands or feet.
  • Change in eyesight, eye pain, or very bad eye irritation.
  • Redness or irritation of the palms of hands or soles of feet.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Headache.
  • Dizziness.
  • Not able to sleep.
  • Change in nails.
  • Upset stomach or throwing up.
  • Not hungry.
  • Loose stools (diarrhea).
  • Hard stools (constipation).
  • Feeling tired or weak.
  • Belly pain.
  • Eye irritation.
  • Skin irritation.
  • Mouth irritation or mouth sores.
  • Back pain.
  • Muscle or joint pain.
  • Cough.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.
  • To gain the most benefit, do not miss doses.
  • Take as you have been told, even if you feel well.
  • Take after a meal, within 30 minutes.
  • Take with a full glass of water.
  • Swallow whole. Do not chew, break, or crush.

What do I do if I miss a dose?

  • Skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

How do I store and/or throw out this drug?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only your healthcare provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your healthcare provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

Copyright

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