Log in »

Denileukin Diftitox (de ni LOO kin DIF ti toks)

Warning

  • Some patients have very bad side effects during the infusion. A sudden change in eyesight or in the way you see color may happen. Rapid weight gain, swelling, and low blood pressure may happen.
  • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.

What is this drug used for?

  • It is used to treat skin cancer from lymphoma.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to denileukin diftitox or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are pregnant or may be pregnant. Do not take this drug if you are pregnant.
  • If you are breast-feeding. Do not breast-feed while you take this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell dentists, surgeons, and other doctors that you use this drug.
  • If you have thyroid disease, talk with your doctor.
  • Have your blood pressure and heart rate checked often. Talk with your doctor.
  • Have your blood work checked. Talk with your doctor.
  • Talk with your doctor before getting any vaccines. Use with this drug may either raise the chance of an infection or make the vaccine not work as well.
  • Use birth control that you can trust to stop pregnancy while taking this drug.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
  • Trouble breathing.
  • Chest pain or pressure, a fast heartbeat, or passing out.
  • Change in thinking clearly and with logic.
  • A big weight gain or loss.
  • Very upset stomach or throwing up.
  • Very loose stools (diarrhea).
  • Very bad swelling.
  • Any bruising or bleeding.
  • Dark urine or yellow skin or eyes.
  • Feeling very tired or weak.
  • Sudden change in eyesight or in the way you see color.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
  • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
  • Flu-like signs. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain drugs may help.
  • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
  • Loose stools (diarrhea).
  • Not hungry.
  • Itching.
  • Rash.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.
  • It is given as a shot into a vein over a period of time.

How do I store and/or throw out this drug?

  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.

Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only your healthcare provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your healthcare provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

Copyright

All content copyright © 1978-2013 Lexi-Comp Inc. or its respective owners. All Rights Reserved.