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Desmopressin (des moe PRES in)

Adult Medication

Brand Names: U.S.

DDAVP; DDAVP Rhinal Tube; Stimate

Brand Names: Canada

Apo-Desmopressin®; DDAVP; DDAVP Melt; Minirin; Novo-Desmopressin; Octostim; PMS-Desmopressin

What is this drug used for?

  • It is used to help prevent bedwetting.
  • It is used to lower urine output.
  • It is used to treat diabetes insipidus.
  • It is used to treat hemophilia.
  • It is used to treat von Willebrand disease.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take this drug?

All products:

  • If you have an allergy to desmopressin or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: Kidney disease or if you have ever had low sodium levels.

Oral-disintegrating tablet:

  • If you have any of these health problems: Heart problems, liver problems, or Type IIB von Willebrand disease.

Shot:

  • If you have type IIB von Willebrand disease.

Nose:

  • If you have a stuffy nose, scarring on the inside of your nose, or you have trouble breathing through your nose.
  • If you have had any recent nose surgery, injury, ulcers, or sores, talk with your doctor.

Stimate®:

  • If you have type IIB von Willebrand disease.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell dentists, surgeons, and other doctors that you use this drug.
  • Have your blood work checked often. Talk with your doctor.
  • Talk with your doctor before you drink alcohol.
  • This drug may rarely cause very low sodium levels. If not treated, this can be deadly. Talk with the doctor.
  • Talk with your doctor if you have an infection, a fever, loose stools (diarrhea), or are throwing up. Talk with your doctor if you will be out in very hot weather, will be active, or will be changing how much water you drink for any reason.
  • If you are 65 or older, use this drug with care. You could have more side effects.
  • Use with care in children. Talk with the doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

All products:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of low sodium levels like headache, trouble focusing, memory problems, change in thinking clearly and with logic, weakness, seizures, or change in balance.
  • Upset stomach or throwing up.
  • Mood changes.
  • Change in how you act.
  • Hallucinations.
  • Feeling tired or weak.
  • Restlessness.
  • Muscle pain or weakness.
  • Muscle spasm.
  • A big weight gain.
  • Not hungry.
  • Shortness of breath.
  • Very bad headache.
  • Very bad dizziness or passing out.
  • Swelling.
  • Swelling, warmth, numbness, change of color, or pain in a leg or arm.
  • Chest pain or pressure.
  • Coughing up blood.
  • Change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or blurred eyesight.
  • Change in eyesight.
  • A fast heartbeat.
  • A heartbeat that does not feel normal.

Nose:

  • Bad nosebleeds.

Shot:

  • Irritation or swelling where the shot was given.
  • Pain where the shot was given.

What are some other side effects of this drug?

Oral and shot:

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.

Nose:

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Cough.
  • Flushing.
  • Nosebleed.
  • Runny nose.
  • Stuffy nose.
  • Sore throat.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.

All products:

  • Follow what the doctor said about how much liquid to drink and how much to work out.

Oral:

  • Take with or without food.
  • Take at bedtime for bedwetting.

Oral-disintegrating tablet:

  • Be sure your hands are dry before you touch this drug.
  • Place oral-disintegrating tablet on tongue and let melt. Water is not needed. Do not swallow whole. Do not chew, break, or crush.

Nose:

  • Follow how to take this drug as you have been told by your doctor. Do not use more than you were told to use.
  • Do not take this drug by mouth. Use in your nose only. Keep out of your mouth and eyes (may burn).
  • Blow your nose before use.

Nose spray:

  • Prime pump before first use or if not used for more than 1 week.

Shot:

  • It is given as a shot into a vein or into the fatty part of the skin.
  • Your doctor may teach you how to give the shot.
  • Follow how to use carefully.
  • Do not use if the solution is cloudy, leaking, or has particles.
  • Do not use if solution changes color.
  • Throw away needles in a needle/sharp disposal box. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not use 2 doses or extra doses.

How do I store and/or throw out this drug?

Oral:

  • Store at room temperature.
  • Protect from light.
  • Store in a dry place. Do not store in a bathroom.

DDAVP® nose spray and Stimate®:

  • Store upright at room temperature. Do not freeze.
  • Protect from light.
  • Store in a dry place. Do not store in a bathroom.
  • Throw away any part not used after 6 months.

Minirin™:

  • Store in a refrigerator or at room temperature. If stored at room temperature, throw away any part not used after 3 weeks.
  • Store upright with the cap on.
  • Do not freeze.

DDAVP® Rhinal Tube:

  • Store in a refrigerator or at room temperature. If stored at room temperature, throw away any part not used after 3 weeks.
  • Do not freeze.

Shot:

  • Most of the time, this drug will be given in a hospital or doctor’s office. If stored at home, follow how to store as you were told by the doctor.

All products:

  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date

2013-10-28

Copyright

Copyright © 2014 Clinical Drug Information, LLC and Lexi-Comp, Inc.