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Dextromethorphan, Chlorpheniramine, Phenylephrine, and Guaifenesin (deks troe meth OR fan, klor fen IR a meen, fen il EF rin, & gwye FEN e sin)

Adult Medication

Brand Names: U.S.

Chlordex GP [DSC]; Donatussin; Quartuss™ [DSC]

Warning

  • Talk with the doctor before giving this drug to a child. Check all of your child’s drugs, including OTC, with doctor.
  • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.

What is this drug used for?

  • It is used to stop coughing.
  • It is used to ease allergy signs.
  • It is used to treat nose stuffiness.
  • It is used to thin mucus so it can be taken from the body by coughing.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to dextromethorphan, chlorpheniramine, phenylephrine, guaifenesin, or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: Enlarged prostate gland, high blood pressure, or overactive thyroid gland.
  • If you have taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson’s disease like selegiline or rasagiline in the last 14 days. Taking this drug within 14 days of those drugs can cause very bad high blood pressure. Talk with your doctor.
  • If you are breast-feeding. Do not breast-feed while you take this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell dentists, surgeons, and other doctors that you use this drug.
  • This drug is not for coughs due to smoking or lung disease.
  • If you have asthma, talk with your doctor.
  • If you have high blood sugar (diabetes), talk with your doctor.
  • If you have glaucoma, talk with your doctor.
  • If you have heart disease, talk with your doctor.
  • Avoid alcohol or other drugs and natural products that slow your actions.
  • Limit your use of caffeine (for example, tea, coffee, cola) and chocolate. Use with this drug may cause nervousness, shakiness, and a fast heartbeat.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Trouble breathing.
  • Chest pain or pressure, a fast heartbeat, or passing out.
  • Very bad headache.
  • Cough that does not go away.
  • Feeling very tired or weak.
  • Not able to pass urine.
  • Sudden change in eyesight.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
  • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
  • Nervous and excitable.
  • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
  • Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often.
  • Not able to sleep.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.
  • Take with or without food. Take with food if it causes an upset stomach.
  • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
  • Those who have feeding tubes may also use the liquid. Flush the feeding tube before and after this drug is given.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
  • Many times this drug is taken on an as needed basis. Do not take more often than told by the doctor.

How do I store and/or throw out this drug?

  • Store at room temperature.
  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Last Reviewed Date

2013-07-16