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Diphenhydramine (Systemic) (dye fen HYE dra meen)

Brand Names: U.S.

Aler-Dryl [OTC]; Allergy Relief Childrens [OTC]; Allergy Relief [OTC]; Altaryl [OTC]; Anti-Hist Allergy [OTC]; Banophen [OTC]; Benadryl Allergy Childrens [OTC]; Benadryl Allergy [OTC]; Benadryl Dye-Free Allergy [OTC]; Benadryl [OTC]; Complete Allergy Medication [OTC]; Complete Allergy Relief [OTC]; Diphen [OTC]; Diphenhist [OTC]; Genahist [OTC]; Geri-Dryl [OTC]; Nighttime Sleep Aid [OTC]; Nytol Maximum Strength [OTC]; Nytol [OTC]; PediaCare Childrens Allergy [OTC]; Pharbedryl [OTC]; Q-Dryl [OTC]; Quenalin [OTC]; Scot-Tussin Allergy Relief [OTC]; Siladryl Allergy [OTC]; Silphen Cough [OTC]; Simply Allergy [OTC]; Simply Sleep [OTC]; Sleep Tabs [OTC]; Sominex Maximum Strength [OTC]; Sominex [OTC]; Tetra-Formula Nighttime Sleep [OTC]; Total Allergy Medicine [OTC]; Total Allergy [OTC]; Triaminic Cough/Runny Nose [OTC]; ZzzQuil [OTC]

Brand Names: Canada

Allerdryl®; Allernix; Benadryl®; Nytol®; Nytol® Extra Strength; PMS-Diphenhydramine; Simply Sleep®; Sominex®

What is this drug used for?

  • It is used to stop coughing.
  • It is used to ease allergy signs.
  • It is used to help motion sickness.
  • It is used to treat Parkinson’s disease.
  • It is used to treat sleep problems.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to diphenhydramine or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
This drug may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

All products:

  • Tell dentists, surgeons, and other doctors that you use this drug.
  • Do not take more than what your doctor told you to take. Taking more than you are told may raise your chance of very bad side effects.
  • Do not take this drug for longer than you were told by your doctor.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
  • Do not use with other products that have diphenhydramine.
  • Avoid beer, wine, or mixed drinks.
  • Talk with your doctor before you use other drugs and natural products that slow your actions.
  • If you are 65 or older, use this drug with care. You could have more side effects.
  • Use caution in children. Talk with your doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Products for sleep problems:

  • Do not give to a child younger than 12 years of age.

Oral strips:

  • Do not give this drug to a child younger than 4 years of age.

All other products:

  • Different brands of this drug may have different doses for children. Talk with the doctor before giving this drug to a child.
  • Do not use to make a child sleepy. Talk with your doctor.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad dizziness or passing out.
  • Change in balance.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Feeling sleepy.
  • Dizziness.
  • Thickening of mucus in nose or throat.
  • Feeling nervous and excitable.
  • Upset stomach or throwing up.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.

All oral products:

  • Take with or without food. Take with food if it causes an upset stomach.

Products for sleep problems:

  • Take at bedtime.

Chewable tablets and oral-disintegrating tablets:

  • Chew well or let melt in the mouth.
  • If you have PKU, talk with your doctor. Some products have phenylalanine.

Oral strip:

  • Place oral strip on your tongue and let melt.

All liquid products:

  • Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, get an oral syringe, a dropper, a spoon, or a cup (only for older children) from your pharmacist.
  • If you have PKU, talk with your doctor. Some products have phenylalanine.

Shot:

  • It is given as a shot into a muscle or vein.

What do I do if I miss a dose?

All oral products:

  • If you take this drug on a regular basis, take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
  • Many times this drug is taken on an as needed basis. Do not take more often than told by the doctor.

Shot:

  • Call your doctor to find out what to do.

How do I store and/or throw out this drug?

All oral products:

  • Store at room temperature.
  • Protect from light.
  • Store in a dry place. Do not store in a bathroom.

All liquid products:

  • Do not freeze.

Shot:

  • This drug will be given to you in a hospital or doctor’s office. You will not store it at home.

All products:

  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only your healthcare provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your healthcare provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

Copyright

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