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Epinephrine (Systemic, Oral Inhalation) (ep i NEF rin)

Adult Medication

Brand Names: U.S.

Adrenaclick; Adrenalin; Asthmanefrin Refill [OTC]; Asthmanefrin Starter Kit [OTC]; Auvi-Q; EpiPen 2-Pak; EpiPen Jr 2-Pak; Micronefrin [OTC] [DSC]; S2 [OTC]

Brand Names: Canada

Adrenalin; Allerject; Anapen; Anapen Junior; EpiPen; EpiPen Jr; S2; Twinject

What is this drug used for?

  • It is used to treat a very bad allergic response.
  • It is used to open the airways in lung diseases where spasm may cause breathing problems.
  • It is used during eye surgery.
  • It is used when the heart is not beating.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to epinephrine or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

Liquid for breathing in:

  • If you have taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson’s disease like selegiline or rasagiline in the last 14 days. Taking this drug within 14 days of those drugs can cause very bad high blood pressure. Talk with your doctor.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

All products:

  • Tell dentists, surgeons, and other doctors that you use this drug.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

Shot:

  • Do not give into the fingers, hands, or feet. Doing so may lead to lower blood flow in these areas. If this drug is given on accident, get medical help right away.
  • If you are not able to get a breathing attack under control, get help right away.
  • If you are allergic to sulfites, talk with your doctor. Some products have sulfites.
  • If you have high blood sugar (diabetes), you will need to watch your blood sugar closely.
  • If you are 65 or older, use this drug with care. You could have more side effects.

Eye:

  • Bright lights may bother you. Wear sunglasses.

Liquid for breathing in:

  • Call your doctor right away if your normal dose does not work well, if your signs get worse, or if you need to use this drug more often than normal.
  • Avoid use of caffeine (for example, tea, coffee, cola) and chocolate. Use with this drug may cause high blood pressure, nervousness, shakiness, a fast heartbeat, and anxiety.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

All products:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Chest pain or pressure.
  • A fast heartbeat.
  • A heartbeat that does not feel normal.

Shot:

  • Shortness of breath.
  • Feeling very tired or weak.

Liquid for breathing in:

  • Change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or blurred eyesight.
  • Very bad headache.
  • Seizures.

Shot (if given in the vein):

  • This drug may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

All products:

  • Dizziness.
  • Nervous and excitable.
  • Shakiness.

Shot:

  • Upset stomach or throwing up.
  • Anxiety.
  • Restlessness.
  • Feeling tired or weak.
  • Sweating a lot.
  • Pale skin.
  • Headache.

Liquid for breathing in:

  • Not able to sleep.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.

For allergic reasons:

  • It is given as a shot into a muscle or into the fatty part of the skin.
  • Read how to use before an emergency happens.
  • Keep this drug with you at all times. You may want to keep extra ones at work, school, and home.
  • Someone else may have to give the shot. Be sure others know where this drug is stored and how to give it if needed.
  • Never put your fingers or hand over the tip.
  • Do not take off safety release until ready to use.
  • When you are ready to use, take the pen out of the case.
  • Hold pen with tip down.
  • Make a fist around the pen.
  • Pull off safety release.
  • Jab straight into the outer thigh until it clicks and hold for as long as you were told.
  • Do not give into the buttocks.
  • Get medical help right away after using this drug.
  • Put back in the storage case.
  • Take it with you to the hospital.
  • Do not use this drug if the solution changes color, is cloudy, or has particles. Get a new one.
  • Do not use if this drug is out of date. Get a new one.
For other reasons:
  • Your doctor will give this drug.

Liquid for breathing in:

  • For breathing in only as a liquid (solution) by a special machine (nebulizer) into the lungs.
  • Follow how to use as you have been told by your doctor or read the package insert.
  • Do not use if the solution is cloudy, leaking, or has particles.
  • Do not use if solution changes color.

What do I do if I miss a dose?

Shot:

  • Get medical help right away.

Liquid for breathing in:

  • If you take this drug on a regular basis, take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
  • Many times this drug is taken on an as needed basis. Do not take more often than told by the doctor.

How do I store and/or throw out this drug?

Shot (if given in the vein):

  • This drug will be given to you in a hospital or doctor’s office. You will not store it at home.

All other products:

  • Store at room temperature. Do not refrigerate or freeze.
  • Protect from light.
  • Protect from heat.

For allergic reasons:

  • Store in the case you were given.

All products:

  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Copyright

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