Brand Names: U.S.
NexIUM; NexIUM I.V.
Brand Names: Canada
Apo-Esomeprazole; Mylan-Esomeprazole; Nexium; PMS-Esomeprazole DR
What is this drug used for?
- It is used to treat gastroesophageal reflux disease.
- It is used to treat or prevent GI (gastrointestinal) ulcers caused by infection.
- It is used to treat or prevent ulcers of the swallowing tube (esophagus).
- It is used to treat syndromes caused by lots of stomach acid.
- It is used to treat or prevent NSAID-associated gastric ulcers in patients with a history of ulcers.
- It is used to treat heartburn.
- It is used to lower the chance of bleeding ulcers after a certain procedure (endoscopy).
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take this drug?
- If you have an allergy to esomeprazole or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are taking any of these drugs: Atazanavir, clopidogrel, nelfinavir, rifampin, or St. John’s wort.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
- If you have any of these health problems: Black or bloody stools; heartburn with light-headedness, sweating, or dizziness; chest pain; shoulder pain with shortness of breath; pain that spreads to the arms, neck, or shoulders; light-headedness; sweating a lot; throwing up blood; or trouble or pain swallowing food.
What are some things I need to know or do while I take this drug?
- Tell dentists, surgeons, and other doctors that you use this drug.
- Use care if you have risks for soft, brittle bones called osteoporosis (alcohol use, cigarette smoking, other family members with brittle bones, taking drugs to treat seizures, taking steroids).
- This drug may affect certain lab tests. Be sure your doctor and lab workers know you take this drug.
- Call your doctor if you have throat pain, chest pain, very bad belly pain, trouble swallowing, or signs of a bleeding ulcer like black, tarry, or bloody stools, throwing up blood, or throw up that looks like coffee grounds. These may be signs of a worse health problem.
- Take calcium and vitamin D as you were told by your doctor.
- This drug may raise the chance of hip, spine, and wrist fractures in people with weak bones (osteoporosis). The chance may be higher if you take this drug in high doses or for longer than a year, or if you are older than 50 years old. Talk with your doctor.
- Low magnesium levels have rarely happened in people taking drugs like this one for at least 3 months. Most of the time, this has happened after 1 year of care. You will need to have your blood work checked if you will be taking this drug for a long time or if you take certain other drugs like digoxin or water pills. Talk with your doctor.
- Long-term treatment (for instance longer than 3 years) with drugs like this one has rarely caused low vitamin B-12 levels. Talk with the doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
- It may take a few days to see the full effect.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of low magnesium levels like mood changes, muscle pain or weakness, muscle cramps or spasms, seizures, shakiness, not hungry, very bad upset stomach or throwing up, or a heartbeat that does not feel normal.
- Signs of kidney problems like unable to pass urine, change in the amount of urine passed, blood in the urine, or a big weight gain.
- Very bad dizziness or passing out.
- Very bad belly pain.
- Bone pain.
- Fever or chills.
- Sore throat.
- Shortness of breath.
- A big weight loss.
- This drug may raise the chance of a very bad type of loose stools (diarrhea). Call your doctor right away if you have stomach pain or cramps, very loose or watery stools, or bloody stools. Do not try to treat loose stools without first checking with your doctor.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- Irritation where the shot is given.
What are some other side effects of this drug?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.
- Feeling sleepy.
- Belly pain.
- Loose stools (diarrhea).
- Hard stools (constipation).
- Dry mouth.
- Upset stomach.
How is this drug best taken?
Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.
- Take as you have been told, even if you feel well.
- Ask your doctor before you take antacids with this drug.
- Take on an empty stomach before breakfast.
- Swallow whole. Do not chew, break, or crush.
- Take with a full glass of water.
- Do not use for more than 14 days or more often than every 4 months unless told to do so by the doctor.
All other oral products:
- Take 1 hour before a meal.
- Swallow whole. Do not chew, break, or crush.
- You may sprinkle contents of capsule on 1 tablespoon (15 mL) of applesauce. Take right away and do not chew granules.
- Those who have feeding tubes may make a liquid. Empty contents of capsule into a 60 mL syringe with 50 mL of water. Replace plunger and shake for 15 seconds. Flush feeding tube before and after this drug is taken.
- Mix 2.5 mg or 5 mg granules with 1 teaspoon (5 mL) and the 10 mg, 20 mg, or 40 mg granules with 1 tablespoon (15 mL) of water; let them sit for a few minutes. Mix and drink.
- Rinse cup with more water and drink.
- Those who have feeding tubes may make a liquid. Empty contents of packet into syringe with 1 teaspoon or 1 tablespoon (5 or 15 mL) of water. Replace plunger and shake. Let sit for a few minutes. After taking this drug, refill syringe with water, shake, and flush feeding tube.
- It is given as a shot into a vein.
- Your doctor may teach you how to use.
- Follow how to use carefully.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- Throw away needles in a needle/sharp disposal box. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- Do not take more than 1 dose of this drug in the same day.
How do I store and/or throw out this drug?
All oral products:
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Most of the time, this drug will be given in a hospital or doctor’s office. If stored at home, follow how to store as you were told by the doctor.
- Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
General drug facts
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Consumer Information Use and Disclaimer
This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
Last Reviewed Date
Copyright © 2014 Clinical Drug Information, LLC and Lexi-Comp, Inc.