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Lamivudine (la MI vyoo deen)

Pediatric Medication

Brand Names: U.S.

Epivir; Epivir HBV

Brand Names: Canada

3TC; Apo-Lamivudine; Apo-Lamivudine HBV; Heptovir

Warning

  • This drug may rarely cause swollen liver and an acid health problem in the blood. This may be deadly in some cases. The chance may be higher in women, in overweight people, and in people who have taken drugs like this one for a long time. Talk with your child’s doctor.
  • Hepatitis B has gotten worse when this drug was stopped in some people with hepatitis B. Close follow-up for a few months is needed when therapy is stopped in people who have hepatitis B. Do not stop giving this drug to your child without calling your child’s doctor.
  • There is more than 1 brand of this drug. One brand cannot safely be used for the other. Your child’s doctor will tell you about any needed change.

Epivir-HBV:

  • Do not give your child this brand of this drug if your child has HIV infection. The dose of this brand is not enough and HIV may be harder to treat after taking it. HIV testing needs to be done before taking this brand. Talk with your child’s doctor.

What is this drug used for?

  • It is used to treat hepatitis B infection.
  • It is used to treat HIV infection.

Is it safe for my child to take this drug?

  • Not if your child has an allergy to lamivudine or any other part of this drug.
  • Be sure to let the doctor know if your child has any allergies or side effects to drugs, foods, or dyes. Make sure to tell about the allergy and what signs your child had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

What are some things I need to know or do while my child takes this drug?

  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.

All products:

  • Do not run out of this drug.
  • Check all drugs your child is taking with your child’s doctor. This drug may not mix well with some other drugs.
  • Avoid giving your child other drugs and natural products that may slow your child’s actions.
  • If your child has kidney disease, talk with the doctor.
  • If your child is being treated for both hepatitis and AIDS, talk with the doctor.
  • Have your child’s blood work checked often. Talk with your child’s doctor.

Treating HIV infection:

  • If this drug changes for HIV infection, make sure to ask your child’s doctor about hepatitis B care.

Hepatitis B infection:

  • Tell your child’s doctor if your child has never been on hepatitis care before.

What are some side effects that I need to call my child’s doctor about right away?

  • If any of this news causes you to be worried, any of the unwanted side effects happen, or if your child is not better after taking this drug.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
  • If your child shows signs of a very bad reaction, call your child’s doctor or the ER right away. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; swelling of face, lips, tongue, or throat; or if your child is not acting normal.
  • If your child has very bad belly pain.
  • If your child has a very bad upset stomach or is throwing up.
  • If your child has very loose stools (diarrhea).
  • If your child gets a rash.
  • If your child’s health problem does not get better or if you think your child’s health problem is worse.

Treating HIV infection:

  • This drug may help the immune system work. If your child has an infection that you did not know was there, it may show up when your child takes this drug. Tell your child’s doctor right away if you see any signs of infection like fever, sore throat, weakness, cough, or shortness of breath after you start this drug.

What are some other side effects of this drug?

  • Headache.
  • Upset stomach or throwing up. Many small meals and good mouth care may help. Older children may suck hard, sugar-free candy.
  • Loose stools (diarrhea).
  • Irritated pancreas may rarely happen.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read and follow the dosing on the label closely.
  • In HIV care, this drug is most often given with 2 other drugs.
  • To gain the most benefit, do not miss giving your child doses.
  • Give as you have been told, even if your child feels well.
  • Give this drug with or without food. Give with food if it causes an upset stomach.
  • There is a liquid (solution) if your child cannot swallow pills.
  • Children who have feeding tubes may also use the liquid. Flush the feeding tube before and after this drug is given.
  • Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, get an oral syringe, a dropper, a spoon, or a cup (only for older children) from your pharmacist.

What do I do if my child misses a dose?

  • Give a missed dose as soon as you think about it.
  • If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
  • Do not give 2 doses or extra doses.
  • Do not change the dose or stop your child’s drug. Talk with your child’s doctor.

How do I store and/or throw out this drug?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date

2014-04-14

Copyright

Copyright © 2014 Clinical Drug Information, LLC and Lexi-Comp, Inc.