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Lopinavir and Ritonavir (loe PIN a veer & ri TOE na vir)

Pediatric Medication

Brand Names: U.S.

Kaletra

Brand Names: Canada

Kaletra

Warning

  • Sometimes drugs are not safe when your child takes them with other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your child’s doctor about all the drugs your child takes.
  • This drug comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this drug is refilled.

What is this drug used for?

  • It is used to treat HIV infection.

Is it safe for my child to take this drug?

  • Not if your child is younger than 14 days of age.
  • Not if your child has an allergy to lopinavir, ritonavir, or any other part of this drug.
  • Be sure to let the doctor know if your child has any allergies or side effects to drugs, foods, or dyes. Make sure to tell about the allergy and what signs your child had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

What are some things I need to know or do while my child takes this drug?

  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Do not run out of this drug.
  • Have your child wear disease medical alert ID (identification).
  • If your child has high blood sugar (diabetes), talk with the doctor.
  • If your child has heart disease, talk with the doctor.
  • If your child has hemophilia, talk with the doctor.
  • If your child has liver disease, talk with the doctor.
  • If your child has pancreatitis, talk with the doctor.
  • If your child was a premature baby, or is a newborn, talk with the doctor.
  • Check all drugs your child is taking with your child’s doctor. This drug may not mix well with some other drugs.
  • Avoid giving your child other drugs and natural products that may slow your child’s actions.

What are some side effects that I need to call my child’s doctor about right away?

  • If any of this news causes you to be worried, any of the unwanted side effects happen, or if your child is not better after taking this drug.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
  • If your child shows signs of a very bad reaction, call your child’s doctor or the ER right away. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; swelling of face, lips, tongue, or throat; or if your child is not acting normal.
  • If your child has a fast heartbeat.
  • If your child has a slow heartbeat.
  • If your child shows signs of very bad dizziness or passes out.
  • If your child has very bad belly pain.
  • If your child has a very bad upset stomach or is throwing up.
  • If your child is not able to eat.
  • If your child has dark urine or yellow skin or eyes.
  • If your child is feeling very tired or weak.
  • If your child has more trips to the bathroom, more thirst, or weight loss.
  • If your child gets a rash.
  • If your child’s health problem does not get better or if you think your child’s health problem is worse.

What are some other side effects of this drug?

  • High blood sugar may cause diabetes while on this drug. This most often goes back to normal when this drug is stopped.
  • High cholesterol level. Check level before starting this drug.
  • High triglyceride level. Check level before starting this drug.
  • Upset stomach or throwing up. Many small meals and good mouth care may help. Older children may suck hard, sugar-free candy.
  • Belly pain.
  • Loose stools (diarrhea).
  • Harm to the liver may rarely happen.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read and follow the dosing on the label closely.
  • To gain the most benefit, do not miss giving your child doses.
  • Give as you have been told, even if your child feels well.
  • Give tablet with or without food. Give with food if it causes an upset stomach.
  • Have your child swallow tablet whole. Do not let your child chew, break, or crush.
  • There is a liquid (solution) if your child cannot swallow pills.
  • Give liquid with food.
  • Children who have feeding tubes may also use the liquid. Flush the feeding tube before and after this drug is given.
  • Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, get an oral syringe, a dropper, a spoon, or a cup (only for older children) from your pharmacist.

What do I do if my child misses a dose?

  • Give a missed dose as soon as you think about it.
  • If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
  • Do not give 2 doses or extra doses.
  • Do not change the dose or stop your child’s drug. Talk with your child’s doctor.

How do I store and/or throw out this drug?

  • Store tablets at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Store liquid (solution) in a refrigerator or at room temperature. If stored at room temperature, throw away any part not used after 2 months.
  • Protect liquid (solution) from heat.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Copyright

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