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Mesna (MES na)

Pediatric Medication

Brand Names: U.S.

Mesnex

Brand Names: Canada

Mesna for injection; Uromitexan

What is this drug used for?

  • It is used to lower the bad effects of some cancer drugs on the bladder.

Is it safe for my child to take this drug?

  • Not if your child has an allergy to mesna or any other part of this drug.
  • Be sure to let the doctor know if your child has any allergies or side effects to drugs, foods, or dyes. Make sure to tell about the allergy and what signs your child had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

What are some things I need to know or do while my child takes this drug?

All products:

  • Tell dentists, surgeons, and other doctors that your child is using this drug.
  • If your child has an autoimmune disease such as rheumatoid arthritis or lupus, talk with the doctor.
  • If your child has kidney disease, talk with the doctor.
  • Have your child’s urine checked. Talk with your child’s doctor.
  • This drug may affect certain lab tests. Be sure the doctor and lab workers know your child takes this drug.
  • If your child has high blood sugar (diabetes), some urine ketone tests may be wrong. Talk with the doctor.
  • Check all drugs your child is taking with your child’s doctor. This drug may not mix well with some other drugs.

Shot:

  • Some products have benzyl alcohol. Do not give a product that has benzyl alcohol in it to a newborn. Talk with the doctor to see if this product has benzyl alcohol in it.

What are some side effects that I need to call my child’s doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • If your child shows any signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color or sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
  • If your child has any burning or tingling feelings.
  • If your child has very bad flushing.
  • If your child has joint pain or swelling.
  • If your child has very bad muscle pain.
  • If your child is feeling very tired or weak.
  • If your child has shortness of breath.
  • If your child has chest pain or pressure or a fast heartbeat.
  • If your child has blood in the urine.
  • If your child is not able to pass urine.
  • If your child has any bruising or bleeding.
  • If your child has very bad dizziness or passing out.
  • If your child has very loose stools (diarrhea).
  • If your child has a very bad upset stomach or is throwing up.
  • If your child has flu-like signs.
  • A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if your child has signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in the mouth, throat, nose, or eyes.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:

All products:

  • Loose stools (diarrhea).
  • Hard stools (constipation).
  • Upset stomach or throwing up.
  • Dizziness.
  • Feeling sleepy.
  • Not hungry.
  • Hair loss.
  • Headache.
  • Belly pain.
  • Feeling tired or weak.

Shot:

  • Irritation where the shot is given.
These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read and follow the dosing on the label closely.

All products:

  • Have your child drink lots of noncaffeine liquids every day unless told to drink less liquid by your child’s doctor.

Tablets:

  • Tell your child’s doctor if your child throws up within 2 hours of taking an oral dose. Dose may need to be repeated.

Shot:

  • This drug is given as a shot into a vein.

What do I do if my child misses a dose?

  • Call your child’s doctor to find out what to do.

How do I store and/or throw out this drug?

Tablets:

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Throw away any part of oral drug not used.

Shot:

  • This drug will be given to your child in a hospital or doctor’s office. You will not store it at home.

All products:

  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Copyright

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