Brand Names: U.S.
Astramorph; AVINza; Duramorph; Infumorph 200; Infumorph 500; Kadian; MS Contin
Brand Names: Canada
Doloral; Kadian; M-Eslon; M.O.S. 10; M.O.S. 20; M.O.S. 30; M.O.S.-SR; M.O.S.-Sulfate; Morphine Extra Forte Injection; Morphine Forte Injection; Morphine HP; Morphine LP Epidural; Morphine SR; Morphine-EPD; MS Contin; MS Contin SRT; MS-IR; Novo-Morphine SR; PMS-Morphine Sulfate SR; ratio-Morphine; ratio-Morphine SR; Sandoz-Morphine SR; Statex; Teva-Morphine SR
- Even one dose of this drug may be deadly if it is taken by accident. Children are at higher risk. If this drug is taken by accident, get medical help right away.
- Keep all drugs out of the reach of children and pets.
- This drug may be habit-forming with long-term use.
- Misuse or abuse of this drug can lead to overdose and death.
- Do not give your child more of this drug than what the doctor told you to give. Giving more of this drug than you are told may raise the chance of very bad side effects.
- This drug comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this drug is refilled.
If your child is pregnant:
- Using this drug for a long time during pregnancy may cause the unborn baby to become addicted. This can lead to withdrawal in the newborn baby. This can be life-threatening. Talk with the doctor.
- Your child will be watched closely to make sure your child does not misuse, abuse, or become addicted to this drug.
- This drug may cause very bad and sometimes deadly breathing problems. Call the doctor right away if your child has slow, shallow, or trouble breathing.
- The chance of very bad and sometimes deadly breathing problems may be greater when your child first starts this drug or anytime the dose is raised. Talk with your child’s doctor.
- Have your child swallow whole. Do not let your child chew, break, crush, or melt before swallowing. Do not let your child inject or snort this drug. Doing any of these things can cause very bad side effects like trouble breathing and death from overdose.
- If your child cannot swallow this drug whole, you may sprinkle the contents on applesauce. If you do this, have your child swallow the mixture right away without chewing.
Long-acting and liquid products:
- Make sure you have the right drug; there is more than one strength.
- Certain strengths of this drug may only be used by people who have been taking drugs like this drug and are used to their effects. The use of these strengths by people who have not been taking drugs like this drug may cause very bad and sometimes deadly breathing problems. Talk with your doctor.
What is this drug used for?
- It is used to ease very bad pain.
- It is only to be used when around-the-clock (continuous) care is needed for a long time. It is also only to be used when other pain drugs do not treat your child’s pain well enough or your child cannot take them.
All other products:
Is it safe for my child to take this drug?
- Not if your child has an allergy to morphine or any other part of this drug.
- Be sure to let the doctor know if your child has any allergies or side effects to drugs, foods, or dyes. Make sure to tell about the allergy and what signs your child had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- Not if your child has any of these health problems: Very bad lung problems like asthma or trouble breathing, high levels or carbon dioxide in the blood, or stomach or bowel block or narrowing.
- Not if your child has taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine, or drugs used for certain other health problems in the last 14 days. Taking this drug within 14 days of those drugs can cause very bad high blood pressure. Talk with your child’s doctor.
- Not if your child is taking any of these drugs: Buprenorphine, butorphanol, nalbuphine, or pentazocine.
What are some things I need to know or do while my child takes this drug?
- Tell dentists, surgeons, and other doctors that your child is using this drug.
- This drug may be habit-forming with long-term use.
- If your child has been taking this drug for many weeks, talk with your child’s doctor before stopping. You may want to slowly stop this drug.
- If your child is an infant or toddler, use this drug with care.
- If your child has kidney disease, talk with the doctor.
- If your child has liver disease, talk with the doctor.
- If your child has seizures, talk with the doctor.
- Check all drugs your child is taking with your child’s doctor. This drug may not mix well with some other drugs.
- Avoid giving your child other drugs and natural products that may slow your child’s actions.
- Have your child avoid tasks or actions that call for alertness until you see how this drug affects your child. These are things like riding a bike, playing sports, or using items such as scissors, lawnmowers, electric scooters, toy cars, or motorized vehicles.
What are some side effects that I need to call my child’s doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- If any of this news causes you to be worried, any of the unwanted side effects happen, or if your child is not better after taking this drug.
- If your child shows signs of very bad dizziness or passes out.
- If your child has trouble breathing.
- If your child has a change in thinking clearly and with logic.
- If your child is feeling very tired or weak.
- If your child is feeling very nervous and excitable.
- If your child has poor pain control.
- If your child has a very bad upset stomach or is throwing up.
- If your child has very hard stools (constipation).
- If your child gets a rash.
What are some other side effects of this drug?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.
You may report side effects to your national health agency.
- Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Have your child avoid tasks or actions that call for him/her to be alert or have clear eyesight until you see how this drug works.
- To lower the chance of feeling dizzy or passing out, have your child get up slowly over a few minutes when sitting or lying down. Have your child be extra careful climbing stairs.
- Upset stomach or throwing up. Many small meals and good mouth care may help. Older children may suck hard, sugar-free candy.
- Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative.
- Dry mouth. Good mouth care may help. Older children may suck hard, sugar-free candy. Have your child see a dentist often.
How is this drug best given?
Give this drug as ordered by your child’s doctor. Read and follow the dosing on the label closely.
- Do not give this drug with other strong pain drugs or pain patches without talking to your child’s doctor first.
- Give this drug with food to help prevent an upset stomach.
- Have your child swallow long-acting products whole. Do not let your child chew, break, or crush.
- Do not give long-acting products for fast pain relief or on an as needed basis.
- You may sprinkle contents of Kadian® or Avinza® capsule on soft food or liquid. Do not let your child chew.
- There is a liquid if your child cannot swallow pills.
- Children who have feeding tubes may also use the liquid. Flush the feeding tube before and after this drug is given.
- Mix the liquid with fruit juice to make it taste better.
- Make sure you have the right liquid; there is more than one strength.
- Measure liquid doses carefully. Use the measuring device that comes with this drug.
- Have your child drink lots of noncaffeine liquids every day unless told to drink less liquid by your child’s doctor.
- Keep a pain diary.
- It is given as a shot into a muscle, vein, or into the fatty part of the skin.
- Suppositories are for rectal use only.
What do I do if my child misses a dose?
- Give a missed dose as soon as you think about it.
- If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
- Do not give 2 doses at the same time or extra doses.
- Many times this drug is given on an as needed basis. Do not give to your child more often than told by the doctor.
Long-acting products and shot:
- Call your child’s doctor to find out what to do.
How do I store and/or throw out this drug?
- Store at room temperature.
- Protect from light.
- Store in a dry place. Do not store in a bathroom.
- Store suppositories in a refrigerator. Do not freeze.
- The shot will be given to your child in a hospital or doctor’s office. You will not store it at home.
- Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
General drug facts
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Consumer Information Use and Disclaimer
This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
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