Log in »

Nevirapine (ne VYE ra peen)

Pediatric Medication

Brand Names: U.S.

Viramune; Viramune XR

Brand Names: Canada

Auro-Nevirapine; Mylan-Nevirapine; Teva-Nevirapine; Viramune; Viramune XR

Warning

  • Very bad and sometimes deadly liver problems have happened with this drug. The chance is highest within the first 18 weeks of taking this drug but can happen at any time. The chance is highest in women and in people with certain CD4 counts but can happen in men and in people with any CD4 count. Get medical help right away if your child has a rash or signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
  • Do not give this drug to prevent HIV if your child has been exposed to it. It must only be used if your child has HIV. Talk with the doctor.
  • A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if your child has signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in the mouth, throat, nose, or eyes.
  • Your child’s doctor will be watching closely during the first 18 weeks of therapy. If your child has a bad skin reaction, an allergy, or any signs of liver problems, NEVER give him/her nevirapine again.

What is this drug used for?

  • It is used to treat HIV infection.

Is it safe for my child to take this drug?

  • Not if your child has an allergy to nevirapine or any other part of this drug.
  • Be sure to let the doctor know if your child has any allergies or side effects to drugs, foods, or dyes. Make sure to tell about the allergy and what signs your child had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • Not if your child has very bad liver disease.

What are some things I need to know or do while my child takes this drug?

All products:

  • Do not run out of this drug.
  • If your child has had hepatitis, talk with the doctor.
  • If your child has liver disease, talk with the doctor.
  • Have your child’s blood work checked often. Talk with your child’s doctor.
  • Check all drugs your child is taking with your child’s doctor. This drug may not mix well with some other drugs.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Do not give St John’s wort with this drug. This drug may not work as well.
  • Use with care in children. Talk with the doctor.

Extended-release tablets:

  • Do not give this drug to a child younger than 6 years of age.

What are some side effects that I need to call my child’s doctor about right away?

  • If any of this news causes you to be worried, any of the unwanted side effects happen, or if your child is not better after taking this drug.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
  • If your child shows signs of a very bad reaction, call your child’s doctor or the ER right away. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; swelling of face, lips, tongue, or throat; or if your child is not acting normal.
  • If your child is feeling very tired or weak.
  • If your child has very bad belly pain.
  • If your child has a very bad upset stomach or is throwing up.
  • If your child is not able to eat.
  • If your child has very loose stools (diarrhea).
  • If your child has very bad mouth irritation.
  • If your child has very bad muscle pain or weakness.
  • If your child has a sudden change in eyesight, eye pain, or irritation.
  • If your child has very bad skin irritation.
  • If your child gets a rash.
  • If your child’s health problem does not get better or if you think your child’s health problem is worse.

What are some other side effects of this drug?

  • Headache.
  • Upset stomach or throwing up. Many small meals and good mouth care may help. Older children may suck hard, sugar-free candy.
  • Loose stools (diarrhea).
  • Belly pain.
  • Feeling tired or weak.
  • Harm to the liver may rarely happen.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read and follow the dosing on the label closely.

All products:

  • To gain the most benefit, do not miss giving your child doses.
  • Give as you have been told, even if your child feels well.
  • Give this drug with or without food. Give with food if it causes an upset stomach.

Extended-release tablets:

  • Have your child swallow whole. Do not let your child chew, break, or crush.

Liquid (suspension):

  • Shake well before use.
  • Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, get an oral syringe, a dropper, a spoon, or a cup (only for older children) from your pharmacist.

What do I do if my child misses a dose?

  • Give a missed dose as soon as you think about it.
  • If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
  • Do not give 2 doses or extra doses.
  • Do not change the dose or stop your child’s drug. Talk with your child’s doctor.
  • If you miss giving your child 7 days of this drug, call your doctor to find out what to do.

How do I store and/or throw out this drug?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date

2013-02-28

Copyright

Copyright © 2014 Clinical Drug Information, LLC and Lexi-Comp, Inc.