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Ondansetron (on DAN se tron)

Adult Medication

Brand Names: U.S.

Zofran; Zofran ODT; Zuplenz

Brand Names: Canada

Apo-Ondansetron; Ava-Ondansetron; CO Ondansetron; Dom-Ondansetron; JAMP-Ondansetron; Mar-Ondansetron; Mint-Ondansetron; Mylan-Ondansetron; Ondansetron Injection; Ondansetron Injection USP; Ondansetron-Odan; Ondansetron-Omega; Ondissolve ODF; PHL-Ondansetron; PMS-Ondansetron; RAN-Ondansetron; ratio-Ondansetron; Riva-Ondansetron; Sandoz-Ondansetron; Septa-Ondansetron; Teva-Ondansetron; Zofran; Zofran ODT

What is this drug used for?

  • It is used to treat or prevent upset stomach and throwing up.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to ondansetron or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have a long QT on ECG.
  • If you are taking apomorphine.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

All products:

  • Tell dentists, surgeons, and other doctors that you use this drug.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
  • If you are 65 or older, use this drug with care. You could have more side effects.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

Oral-disintegrating tablet:

  • If you have PKU, talk with your doctor. Some products have phenylalanine.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Chest pain or pressure or passing out.
  • Slow heartbeat.
  • Numbness and tingling.
  • Belly pain.
  • Trouble passing urine.
  • Trouble controlling body movements.
  • Change in eyesight.
  • Agitation, twitching, sweating, or muscle stiffness.
  • Feeling very sleepy.
  • A very bad and sometimes deadly health problem called serotonin syndrome may happen. The risk may be greater if you take this drug with certain other drugs. Call your doctor right away if you have dizziness, very bad headache, agitation, hallucinations, fever, fast heartbeat, a heartbeat that does not feel normal, flushing, seizures, shakiness, sweating a lot, change in balance, change in thinking clearly and with logic, very bad upset stomach and throwing up, or very bad loose stools.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Headache.
  • Feeling tired or weak.
  • Hard stools (constipation).
  • Feeling sleepy.
  • Dizziness.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.

All oral products:

  • Take with or without food.

Oral-disintegrating tablet:

  • Open right before use.
  • Do not push the tablet out of the foil when opening. Use dry hands to take it from the foil. Place on your tongue and let it melt. Water is not needed. Do not swallow it whole. Do not chew, break, or crush it.

Oral film:

  • Open right before use.
  • Put film on tongue and let it melt. Water is not needed. If using more than 1 film, let each film melt all the way before using the next film.
  • Do not chew this drug.
  • Do not swallow it whole.
  • Wash your hands after use.

Liquid (solution):

  • Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, get an oral syringe, a dropper, a spoon, or a cup (only for older children) from your pharmacist.

Shot:

  • It is given as a shot into a vein.
  • Your doctor may teach you how to give the shot.
  • Follow how to use carefully.
  • Do not use if the solution is cloudy, leaking, or has particles.
  • Do not use if solution changes color.
  • Throw away needles in a needle/sharp disposal box. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.

What do I do if I miss a dose?

  • If you take this drug on a regular basis, take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
  • Many times this drug is taken on an as needed basis. Do not take more often than told by the doctor.

How do I store and/or throw out this drug?

All oral products:

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Protect from light.

Oral film:

  • Store in original container.

Liquid (solution):

  • Store upright with the cap on.

Shot:

  • Most of the time, this drug will be given in a hospital or doctor’s office. If stored at home, follow how to store as you were told by the doctor.

All products:

  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date

2014-10-03

Copyright

Copyright © 2014 Clinical Drug Information, LLC and Lexi-Comp, Inc.