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Propafenone (pro PAF en one)

Brand Names: U.S.

Rythmol; Rythmol SR

Brand Names: Canada

Apo-Propafenone®; Mylan-Propafenone; PMS-Propafenone; Rythmol® Gen-Propafenone

Warning

  • This drug is only to be used to treat life-threatening abnormal heartbeats. It may cause very bad and sometimes deadly side effects. Talk with your doctor.

What is this drug used for?

  • It is used to treat heartbeats that are not normal.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to propafenone or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: Breathing problems, Brugada syndrome, electrolyte problems in your blood, low blood pressure, recent heart attack, slow heartbeat without a working pacemaker, or weak heart.
  • If you are taking any of these drugs: QTc-prolonging drugs like amiodarone, arsenic trioxide, chlorpromazine, cisapride, dofetilide, dolasetron, droperidol, mefloquine, moxifloxacin, pentamidine, pimozide, procainamide, quinidine, sotalol, tacrolimus, and thioridazine. Ask your doctor if you are not sure.
  • If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with this drug, like certain drugs that are used for HIV, infections, or depression. There are many drugs that must not be taken with this drug.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell dentists, surgeons, and other doctors that you use this drug.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
  • Have your blood work checked. Talk with your doctor.
  • This drug may affect certain lab tests. Be sure your doctor and lab workers know you take this drug.
  • You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
  • This drug may lower sperm counts in men. This may affect being able to father a child. Talk with the doctor.
  • If you have a pacemaker, talk with your doctor.
  • You will need an ECG before starting this drug.
  • Have an ECG checked often. Talk with your doctor.
  • Avoid grapefruit and grapefruit juice.
  • Tell your doctor if you have too much sweat, fluid loss, throwing up, loose stools (diarrhea), not hungry, or more thirst.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
  • Chest pain or pressure.
  • Fast or slow heartbeat.
  • Very bad dizziness or passing out.
  • Very bad headache.
  • Very upset stomach or throwing up.
  • Swelling, warmth, numbness, change of color, or pain in a leg or arm.
  • A big weight gain.
  • Black, tarry stools.
  • Blood in the urine.
  • A burning, numbness, or tingling feeling that is not normal.
  • Not able to pass urine or change in how much urine is passed.
  • Pain when passing urine.
  • Change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or blurred eyesight.
  • Change in hearing.
  • Mood changes.
  • Muscle pain or weakness.
  • A new or worse heartbeat that does not feel normal.
  • Ringing in ears.
  • Feeling very tired or weak.
  • Shortness of breath.
  • Very bad belly pain.
  • Very bad back pain.
  • Swelling in the arms or legs.
  • Shakiness.
  • Not able to sleep.
  • Any bruising or bleeding.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Dizziness.
  • A heartbeat that does not feel normal.
  • Upset stomach.
  • Feeling tired or weak.
  • Hard stools (constipation).
  • Change in taste.
  • Feeling sleepy.
  • Dry mouth.
  • Gas.
  • Headache.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.

All products:

  • Take with or without food. Always take with food or always take on an empty stomach.
  • Take as you have been told, even if you feel well.
  • Take this drug at the same time of day.

Long-acting capsules:

  • Swallow whole. Do not chew, break, or crush.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
  • Do not change the dose or stop this drug. Talk with the doctor.

How do I store and/or throw out this drug?

  • Store at room temperature.
  • Protect from light.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only your healthcare provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your healthcare provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

Copyright

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