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Radium Ra 223 Dichloride (RAY dee um R A two twenty-three dye KLOR ide)

Adult Medication

Brand Names: U.S.

Xofigo

What is this drug used for?

  • It is used to treat prostate cancer.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to radium Ra 223 dichloride or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are pregnant or may be pregnant. Do not take this drug if you are pregnant.
  • If you are taking chemotherapy or other kinds of cancer treatment.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell dentists, surgeons, and other doctors that you use this drug.
  • Have your blood work checked. Talk with your doctor.
  • Use care to keep body fluids from coming in contact with family members or caregivers. Wash soiled clothing right away and use gloves when touching body fluids.
  • Use the same toilet each time you use the bathroom in your home. Sit down on the toilet to urinate to keep urine from splashing or spraying. Flush the toilet a few times after each use.
  • This drug may raise the chance of bone cancer and other types of cancer. Talk with your doctor.
  • If you are a man and have sex with a woman who can get pregnant, protect your partner from pregnancy. Use a latex condom during care and for 6 months after stopping this drug. Your female partner must also use birth control that you can trust to stop pregnancy during care and for 6 months after you stop this drug.
  • This drug may cause harm to the unborn baby if you take it while you are pregnant.
  • If you get pregnant while taking this drug, call your doctor right away.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
  • This drug is not approved for use in women.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
  • Very upset stomach or throwing up.
  • Very loose stools (diarrhea).
  • Too much sweat or fluid loss.
  • Swelling in the arms or legs.
  • Not able to pass urine.
  • This drug may lower the ability of your bone marrow to make blood cells that your body needs. This can lead to very bad and sometimes deadly bleeding problems or infections. Tell your doctor right away if you have signs of infection like fever, chills, or sore throat; any bruising or bleeding; or if you feel very tired or weak.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Upset stomach or throwing up.
  • Loose stools (diarrhea).
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.
  • It is given as a shot into a vein.
  • Drink lots of noncaffeine liquids after the test is over unless told to drink less liquid by your doctor.

How do I store and/or throw out this drug?

  • This drug will be given to you in a hospital or doctor’s office. You will not store it at home.
  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Copyright

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