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Rifampin (rif AM pin)

Adult Medication

Brand Names: U.S.

Rifadin

Brand Names: Canada

Rifadin®; Rofact™

What is this drug used for?

  • It is used to treat TB (tuberculosis).
  • It is used to stop the spread of meningitis in people who carry the bacteria but are not sick with the disease.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to rifampin or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are taking any of these drugs: Atazanavir, darunavir, fosamprenavir, saquinavir, or tipranavir.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell dentists, surgeons, and other doctors that you use this drug.
  • Have your blood work checked often. Talk with your doctor.
  • This drug may affect certain lab tests. Be sure your doctor and lab workers know you take this drug.
  • Talk with your doctor before you drink alcohol.
  • If you have high blood sugar (diabetes), you will need to watch your blood sugar closely.
  • This drug may stain contact lenses.
  • Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also like a condom when taking this drug.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

All products:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Feeling very tired or weak.
  • Not able to pass urine or change in how much urine is passed.
  • Blood in the urine.
  • Change in thinking clearly and with logic.
  • Flu-like signs.
  • Fever or chills.
  • Sore throat.
  • Joint pain or swelling.
  • Muscle pain or weakness.
  • Shortness of breath.
  • Swelling in the arms or legs.
  • Any bruising or bleeding.
  • Change in balance.
  • Not able to focus.
  • Change in how you act.
  • Period (menstrual) changes.
  • Change in eyesight.
  • It is common to have loose stools (diarrhea) when taking this drug. Rarely, a very bad and sometimes deadly form of loose stools may occur (pseudomembranous colitis). This may happen while you are taking this drug or within a few months after you stop taking it. Call your doctor right away if you have stomach pain or cramps, very loose or watery stools, or bloody stools. Do not try to treat loose stools without first checking with your doctor.
  • Very bad and sometimes deadly liver problems have happened with this drug. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.

Shot:

  • Pain where the shot was given.
  • Redness or swelling where the shot is given.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Loose stools (diarrhea).
  • Dizziness.
  • Feeling sleepy.
  • Gas.
  • Headache.
  • Upset stomach or throwing up.
  • Not hungry.
  • Heartburn.
  • Feeling tired or weak.
  • Change in color of body fluids to orange or red.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.

All products:

  • To gain the most benefit, do not miss doses.
  • Take as you have been told, even if you feel well.

Capsule:

  • Take on an empty stomach. Take 1 hour before or 2 hours after meals.
  • Take with a full glass of water.
  • Do not take antacids within 1 hour of this drug.
  • A liquid (suspension) can be made if you cannot swallow pills. Talk with your doctor or pharmacist.

Liquid (suspension):

  • Shake well before use.
  • Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, get an oral syringe, a dropper, a spoon, or a cup (only for older children) from your pharmacist.

Shot:

  • It is given as a shot into a vein.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

How do I store and/or throw out this drug?

Capsule:

  • Store at room temperature.
  • Protect from heat.
  • Store in a dry place. Do not store in a bathroom.

Liquid (suspension):

  • Store liquid (suspension) at room temperature or in a refrigerator. Throw away any unused portion after 4 weeks.

Shot:

  • This drug will be given to you in a hospital or doctor’s office. You will not store it at home.

All products:

  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date

2014-04-28

Copyright

Copyright © 2014 Clinical Drug Information, LLC and Lexi-Comp, Inc.