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Rizatriptan (rye za TRIP tan)

Adult Medication

Brand Names: U.S.

Maxalt; Maxalt-MLT

Brand Names: Canada

Apo-Rizatriptan; Apo-Rizatriptan RPD; CO Rizatriptan; CO Rizatriptan ODT; Dom-Rizatriptan RDT; JAMP-Rizatriptan; Mar-Rizatriptan; Maxalt; Maxalt RPD; Mylan-Rizatriptan ODT; PMS-Rizatriptan RDT; Riva-Rizatriptan ODT; Rizatriptan RDT; Sandoz-Rizatriptan ODT

What is this drug used for?

  • It is used to treat migraine headaches.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to rizatriptan or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: High blood pressure or some types of migraine headaches like hemiplegic or basilar migraine.
  • If you have ever had any of these health problems: Chest pain or pressure; diseased arteries going to the legs or arms; heart attack; heart disease; poor blood flow in the heart, brain, bowel, or kidney; stroke; or a heartbeat that is not normal like Wolff-Parkinson-White syndrome.
  • If you are using this drug to prevent migraine headaches.
  • If you have taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson’s disease like selegiline or rasagiline in the last 14 days. Taking this drug within 14 days of those drugs can cause very bad high blood pressure. Talk with your doctor.
  • If you have taken almotriptan, eletriptan, frovatriptan, naratriptan, sumatriptan, or zolmitriptan in the last 24 hours.
  • If you have taken ergotamine, methysergide, dihydroergotamine, or any drug like them in the last 24 hours.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

All products:

  • Tell dentists, surgeons, and other doctors that you use this drug.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
  • Use care if you have risks for heart disease (high blood pressure, high cholesterol, overweight, high blood sugar [diabetes], cigarette smoking, man older than 40 years of age, other family members with early heart disease, woman after change of life). Talk with your doctor.
  • Taking more of this drug (a higher dose, more often) than your doctor told you to take may cause your headaches to become worse.
  • If you are 65 or older, use this drug with care. You could have more side effects.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

Oral-disintegrating tablet:

  • If you have PKU, talk with your doctor. Some products have phenylalanine.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad headache or if headache is not better after the first dose.
  • Change in eyesight.
  • Loss of eyesight. This can be long-lasting.
  • Hard stools (constipation).
  • Loose stools (diarrhea).
  • Very upset stomach or throwing up.
  • Very bad belly pain or bloody loose stools.
  • Fever.
  • Weight loss.
  • Leg cramps.
  • Feeling of heaviness or tightness in your leg muscles.
  • Feeling cold.
  • Burning or aching pain in your feet or toes.
  • Shortness of breath.
  • Mood changes.
  • Change in color of skin.
  • A very bad and sometimes deadly health problem called serotonin syndrome may happen. The risk may be greater if you take this drug with certain other drugs. Call your doctor right away if you have dizziness, very bad headache, agitation, hallucinations, fever, fast heartbeat, a heartbeat that does not feel normal, flushing, seizures, shakiness, sweating a lot, change in balance, change in thinking clearly and with logic, very bad upset stomach and throwing up, or very bad loose stools.
  • Very bad and sometimes deadly heart problems like heart attack and a heartbeat that is not normal have rarely happened within a few hours of taking this drug. Call your doctor right away if you have chest, throat, neck, or jaw tightness, pain, pressure, or heaviness; break out in a cold sweat; shortness of breath; a fast heartbeat; a heartbeat that does not feel normal; or very bad dizziness or passing out.
  • Very bad and sometimes deadly brain blood vessel problems like stroke have rarely happened with this drug. Call your doctor right away if you have a change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or change in eyesight.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Dizziness.
  • Feeling sleepy.
  • Feeling of heaviness or pressure.
  • A burning, numbness, or tingling feeling that is not normal.
  • Upset stomach or throwing up.
  • Feeling tired or weak.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.

All products:

  • Take with or without food.

Adults:

  • If your headache comes back after the first dose, 1 more dose may be taken 2 hours after the first one.

Tablet:

  • Swallow whole. Do not chew, break, or crush.
  • Take with liquids as early as you can after the attack has started.

Oral-disintegrating tablet:

  • Use right after opening.
  • Do not push the tablet out of the foil when opening. Use dry hands to take it from the foil. Place on your tongue and let it melt. Water is not needed. Do not swallow it whole. Do not chew, break, or crush it.
  • Take as early as you can after the attack has started.

What do I do if I miss a dose?

  • This drug is taken on an as needed basis. Do not take more often than told by the doctor.

How do I store and/or throw out this drug?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Copyright

Copyright © 2014 Clinical Drug Information, LLC and Lexi-Comp, Inc.