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Sargramostim (sar GRAM oh stim)

Pediatric Medication

Brand Names: U.S.

Leukine

Brand Names: Canada

Leukine

What is this drug used for?

  • It is used to treat cancer patients who have had bone marrow problems caused by chemo.
  • It is used to treat low white blood cell counts.

Is it safe for my child to take this drug?

  • Not if your child has an allergy to sargramostim or any other part of this drug.
  • Be sure to let the doctor know if your child has any allergies or side effects to drugs, foods, or dyes. Make sure to tell about the allergy and what signs your child had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • Do not give this drug to your child on the same day that he/she gets chemo or radiation.

What are some things I need to know or do while my child takes this drug?

  • If your child has lung disease, talk with the doctor.
  • If your child has a weak heart, talk with the doctor.
  • Have your child’s blood work checked. The dose of this drug may be changed depending on the results. Talk with your child’s doctor.
  • Some products have benzyl alcohol. Do not give a product that has benzyl alcohol in it to a newborn. Talk with the doctor to see if this product has benzyl alcohol in it.
  • Check all drugs your child is taking with your child’s doctor. This drug may not mix well with some other drugs.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.

What are some side effects that I need to call my child’s doctor about right away?

  • If any of this news causes you to be worried, any of the unwanted side effects happen, or if your child is not better after taking this drug.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
  • If your child shows signs of a very bad reaction, call your child’s doctor or the ER right away. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; swelling of face, lips, tongue, or throat; or if your child is not acting normal.
  • If your child shows signs of very bad dizziness or passes out.
  • If your child has a fast heartbeat.
  • If your child has trouble breathing.
  • If your child has swelling in his/her legs or belly.
  • If your child has very loose stools (diarrhea).
  • If your child has a big weight gain.
  • If your child gets a rash.
  • If your child’s health problem does not get better or if you think your child’s health problem is worse.

What are some other side effects of this drug?

  • Irritation where the shot is given.
  • Headache.
  • Fever and chills.
  • Not able to sleep.
  • Swelling in the feet or hands.
  • Bone pain. You may be given drugs before this shot to avoid these signs.
  • Aches and pains. Mild pain drugs may help.
  • Feeling tired or weak.
  • High blood pressure.
  • Low blood pressure, a fast heartbeat, flushing, and passing out may rarely happen with the first dose.
  • Loose stools (diarrhea).
  • Unsafe allergic effects may rarely happen.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read and follow the dosing on the label closely.
  • It is given as a shot into the fatty part of the skin.
  • It is given into a vein for a period of time.

What do I do if my child misses a dose?

  • Call your doctor for an office visit.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

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