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Sodium Polystyrene Sulfonate (SOW dee um pol ee STYE reen SUL fon ate)

Adult Medication

Brand Names: U.S.

Kalexate; Kayexalate; Kionex; SPS

Brand Names: Canada

Kayexalate®; PMS-Sodium Polystyrene Sulfonate

What is this drug used for?

  • It is used to treat high potassium levels.

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to sodium polystyrene sulfonate or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: Hard stools (constipation), low potassium levels, or if you have not had a bowel movement after surgery.
  • If you have ever had any of these health problems: Bowel block, bowel disease, bowel surgery, not able to have a bowel movement, or long-term hard stools (constipation).
  • If you are taking any of these drugs: Magnesium hydroxide or sorbitol.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell dentists, surgeons, and other doctors that you use this drug.
  • If you are on a low-salt diet (this drug has salt), talk with your doctor.
  • Have your blood work checked. Talk with your doctor.
  • If you are taking a salt substitute that has potassium, potassium-sparing diuretics, or potassium, talk with your doctor.
  • If you are 65 or older, use this drug with care. You could have more side effects.
  • Use with care in children. Talk with the doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of low potassium levels like muscle pain or weakness, muscle cramps, or a heartbeat that does not feel normal.
  • Mood changes.
  • Change in the way you act.
  • Change in thinking clearly and with logic.
  • Dizziness.
  • Fast or slow heartbeat.
  • Seizures.
  • Very loose stools (diarrhea).
  • Swelling in the arms or legs.
  • Very bad and sometimes deadly bowel problems like bleeding, swelling, and tearing have happened with this drug. Most people who had these problems were also taking sorbitol. The chance of these problems may be raised if you have low blood volume, kidney disease, or if you have ever had bowel disease or surgery. Call your doctor right away if you have black, tarry, or bloody stools; hard stools (constipation); belly pain; swelling of the stomach; or throwing up blood or throw up that looks like coffee grounds.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Not hungry.
  • Upset stomach or throwing up.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read and follow the dosing on the label closely.

All products:

  • Most of the time, this drug will be given in a doctor’s office.
  • Your doctor may teach you how to use.
  • Follow how to use carefully.
  • It may be given by mouth or given rectally.

Liquid (suspension):

  • Shake well before use.

Powder:

  • Mix powder with liquid. Ask your doctor how much liquid you need to use. Shake or mix well.
  • Use the solution within 24 hours.

Rectal:

  • Keep suspension in your rectum as long as you can.

What do I do if I miss a dose?

  • Many times this drug is used on an as needed basis. Do not use more often than told by the doctor.
  • Call the doctor to find out what to do.

How do I store and/or throw out this drug?

All products:

  • Store at room temperature.
  • Protect from heat.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

Liquid (suspension):

  • Do not freeze.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Copyright

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