Log in »

Tretinoin (Systemic) (TRET i noyn)

Pediatric Medication

Brand Names: Canada

Vesanoid

Warning

  • This drug may cause a high white blood cell count. Your child will be closely watched by the doctor.
  • This drug may cause a very bad and sometimes deadly health problem called retinoic-acid-APL syndrome. Most of the time, this problem happens during the first month of taking this drug and sometimes after the first dose. Call the doctor right away if your child has a fever; shortness of breath or trouble breathing; swelling; weight gain; very bad dizziness or passing out; signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes; or signs of kidney problems like not able to pass urine, change in how much urine is passed, or blood in the urine.
  • Sometimes drugs are not safe when your child takes them with other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your child’s doctor about all the drugs your child takes.

What is this drug used for?

  • It is used to treat leukemia.

Is it safe for my child to take this drug?

  • Not if your child has an allergy to tretinoin, vitamin A, or any other part of this drug.
  • Tell the doctor if your child is allergic to any drug. Make sure to tell about the allergy and how it affected your child. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

What are some things I need to know or do while my child takes this drug?

  • If your child has high cholesterol or triglyceride levels, talk with the doctor.
  • Have your child’s blood work checked. Talk with your child’s doctor.
  • Check all drugs your child is taking with your child’s doctor. This drug may not mix well with some other drugs.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Avoid other sources of vitamin A.
  • Your child may bleed or clot more easily. Have him/her be more careful and avoid injury. Keep your child from rough-housing or playing contact sports.
  • Talk with the doctor before giving your child products that have aspirin, ibuprofen or like products, blood thinners (warfarin, ticlopidine, clopidogrel), garlic, ginseng, ginkgo, or vitamin E.
  • Your child may get sunburned more easily. Avoid lots of sun, sunlamps, and tanning beds. Use sunscreen and dress your child in clothing and eyewear that protects him/her from the sun.
  • Take care of your child’s teeth. See a dentist often.

What are some side effects that I need to call my child’s doctor about right away?

  • If any of this news causes you to be worried or if any of the unwanted side effects happen after your child is given this drug.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
  • If your child shows signs of a very bad reaction, call your child’s doctor or the ER right away. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; swelling of face, lips, tongue, or throat; or if your child is not acting normal.
  • If your child has trouble breathing.
  • If your child has a bad headache.
  • If your child has a very bad upset stomach or is throwing up.
  • If your child has any bruising or bleeding.
  • If your child has a sudden change in eyesight, eye pain, or irritation.
  • If your child gets a rash.
  • If your child’s health problem does not get better or if you think your child’s health problem is worse.

What are some other side effects of this drug?

  • Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Have your child avoid tasks or actions that call for him/her to be alert or have clear eyesight until you see how this drug works.
  • Flushing. Dressing your child in layers of clothes or summer clothes and providing a cool place may help.
  • Upset stomach or throwing up. Many small meals and good mouth care may help. Older children may suck hard, sugar-free candy.
  • High or low blood pressure.
  • Headache.
  • Fever.
  • Belly pain.
  • Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative.
  • Loose stools (diarrhea).
  • Swelling.
  • Bone pain.
  • Skin irritation.
  • Sunburn.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read and follow the dosing on the label closely.
  • Give this drug with food.
  • Have your child swallow capsule whole. Do not let your child chew, break, or crush.

What do I do if my child misses a dose?

  • Give a missed dose as soon as you think about it.
  • If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
  • Do not give 2 doses or extra doses.
  • Do not change the dose or stop your child’s drug. Talk with your child’s doctor.

How do I store and/or throw out this drug?

  • Store at room temperature.
  • Protect from light.
  • Store in a dry place. Do not store in a bathroom.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Copyright

Copyright © 2014 Clinical Drug Information, LLC and Lexi-Comp, Inc.