Ependymomas are tumors of the brain or spinal cord. Carboplatin is a drug commonly used to treat several types of cancer. Bevacizumab is a drug that works by inhibiting the growth of the blood vessels that tumors need to grow and spread. In this study, investigators are assessing the safety and effectiveness of combination therapy with carboplatin and bevacizumab in patients with ependymoma of the brain or spinal cord.
Bevacizumab is approved for treating gliomas and other cancers, but its use in combination with carboplatin in patients with ependymoma is considered investigational.