External beam radiation therapy and brachytherapy are options for the initial treatment of localized prostate cancer. Brachytherapy involves the implantation of tiny radioactive seeds near the tumor.
In this Radiation Therapy Oncology Group study, researchers are evaluating the effectiveness and side effects of brachytherapy when used in men with prostate cancer that has returned despite previous external beam radiation therapy. The radiation dose to be used in this study is slightly lower than that used in standard initial brachytherapy. Doctors are extra cautious about exposing nearby healthy tissue to radiation, since patients have already received prior radiation therapy to the prostate.