The standard therapy for limited small cell lung cancer is chemotherapy with cisplatin and etoposide every three weeks, plus radiation therapy twice a day for three weeks. In this study, researchers want to study two other chemoradiation regimens with the standard therapy to compare their effectiveness and their side effects.
Patients will be randomly assigned to receive the standard treatment regimen or one of two investigational regimens. In one investigational regimen, radiation therapy is given once a day for seven weeks. In the second investigational regimen, patients receive radiation once a day for 16 days of treatment (about three weeks), followed by radiation twice a day for the remaining 9 days of treatment (about two weeks), for a total of five weeks. Patients in all three study groups will receive cisplatin and etoposide every three weeks.