Urothelial cancers affect the urinary system. This study is being done to create a registry to learn more about these cancers, enabling researchers to look at large groups of people with and without this kind of cancer.
Researchers will look at risk factors to learn more about their relationship to cancer. They will also look at genetic markers in saliva which may be associated with a particular trait. It is hoped that certain genes identified in patients may predict cancer risk or response to treatment.
This registry may lead to better methods of preventing, diagnosing, and treating urothelial cancers. Participants will include those with and without urothelial cancers. They will be asked to complete a questionnaire about risk factors (such as smoking, occupational exposures, alcohol use, and family medical history) and provide samples such as saliva and/or blood, and (in the case of people with urothelial cancer who are having a biopsy or surgery) tumor tissue.