Familial adenomatous polyposis (FAP) is a genetic condition which causes the growth of many small growths in the colon, especially as people with FAP get older. These polyps do not start out to be cancerous, but as they grow they often develop into cancer.
The purpose of this study is to determine if giving the drug celecoxib (Celebrex) to children and adolescents with FAP can keep the number and size of polyps to a level that would delay or even prevent the need for a colectomy (surgical removal of part of the bowel). Another goal of the study is to see if celecoxib can be used safely in children with the genetic mutation that causes FAP when taken over a period of five years.
Participants in this study will receive celecoxib or a placebo.