Protocol
11-100
Full Title
Cardiac-Sparing Whole Lung IMRT in Children and Young Adults with Lung Metastases: A Feasibility Study
Purpose
Conventional external beam radiation therapy to the lungs is delivered via two beams — one from the front, one from the back — but exposes other organs in the chest, such as the heart, to radiation. Intensity-modulated radiation therapy (IMRT) is a more targeted way to direct multiple radiation beams contoured to the shape and density of a tumor, and spares more of the heart and other nearby healthy tissues from radiation.
In this study, researchers want to assess the safety and feasibility of giving IMRT to children and young adults with Ewing’s sarcoma, Wilms tumor, or rhabdomyosarcoma that has spread to the lungs. Patients will be treated with either conventional radiation therapy or IMRT, and researchers will compare the two groups.
Investigator
Co-Investigators
Yorke, Ellen, PhD
Eligibility
To be eligible for this study, patients must meet several criteria, including but not limited to the following:
- Patients must be older than age 12 months but younger than 30 years.
- Patients must have lung metastases from Ewing’s sarcoma, Wilms tumor, or rhabdomyosarcoma.
- Patients may not have previously received radiation therapy to the chest.
For more information about this study and to inquire about eligibility, please contact Dr. Suzanne Wolden at 212-639-5148.
Disease(s)
Primary Bone: Ewing's Sarcoma
Sarcomas
Sarcomas: Ewing's Sarcoma
Sarcomas: Rhabdomyosarcoma
Locations
Related Diseases
