PI3K and mTOR are two different proteins found to promote the growth of cancer. DS-7423 is an investigational drug that works by inhibiting both PI3K and mTOR. Doctors hope that blocking these proteins can shrink tumors.
In this study, investigators want to find the highest dose of DS-7423 that can be given safely in patients with advanced solid tumors that persist despite standard therapy or for which no standard therapy exists. DS-7423 is a capsule that is taken orally (by mouth).