Chemotherapy and radiation therapy for lung cancer may cause painful inflammation of the esophagus (esophagitis). This pain can make it uncomfortable for patients to swallow and make eating difficult.
In clinical studies, honey has been shown to be an effective wound dressing and to prevent blistering of the mouth that can occur during radiation treatment. In this Radiation Therapy Oncology Group study, researchers want to see if a medicinal honey, called Manuka honey, can prevent or delay the onset of esophagitis in patients receiving chemotherapy and radiation therapy for lung cancer.
Patients in this study will be randomly assigned to one of three groups: standard supportive care (pain-relieving medication), the honey in liquid form, or the honey in lozenge form.