Radiation therapy plus the chemotherapy drug cisplatin (“chemoradiation”) is the standard treatment for cervical cancer that has spread beyond the cervix. The purpose of this study is to see if adding the drugs carboplatin and paclitaxel after chemoradiation reduces the risk of cancer recurrence and improves patient survival.
Patients will be randomly assigned to receive chemoradiation alone, or chemoradiation plus carboplatin and paclitaxel. Researchers will compare the two groups with respect to cancer recurrence rate, survival, and quality of life.
This study is being conducted by the Gynecologic Oncology Group and the Radiation Therapy Oncology Group.