Surgery remains the main treatment of brain tumors. The goal of brain tumor surgery is to maximize tumor resection without damaging important adjacent brain structures (called eloquent cortices), which include parts of the brain that control speech, movement, and vision. Inadvertent resection of one of these areas leads to devastating consequences such as paralysis or blindness. Functional MRI (fMRI) is a non-invasive method currently used to study many diverse brain functions. Neurosurgical navigational systems based on fMRI have been proposed as a reliable system that could display the relationship between the tumor and the adjacent eloquent cortex both pre- and intra-operatively in 3-D and in real-time. We test the accuracy of fMRI in brain tumor patients including technical limitations of fMRI as a method due to the presence of neovasculature. We also study cortical reorganization due to the growth of a brain tumor.
Basic Science, Clinical Research, and Translational Research
Preferred Project Dates
- June 15 – August 7
- June 22 – August 14